التفاصيل البيبلوغرافية
العنوان: |
The association of 18F-FDG PET/CT and biomarkers in confirming coronary microvascular dysfunction. |
المؤلفون: |
Mayala, Henry Anselmo, Bakari, Khamis Hassan, Mkangala, Abdalah, Magesa, Mafuru, Mghanga, Fabian Pius, ZhaoHui, Wang |
المصدر: |
BMC Research Notes; 11/6/2018, Vol. 11 Issue 1, pN.PAG-N.PAG, 1p, 1 Diagram, 2 Charts |
مصطلحات موضوعية: |
MICROCIRCULATION disorders, CORONARY disease, BRAIN natriuretic factor, ERYTHROCYTES, POSITRON emission tomography |
مستخلص: |
Objective: The purpose of this study is to evaluate the association between PET/CT CFR and biomarkers combined in confirming the diagnosis of coronary microvascular dysfunction. Results: A total of 28 patients (21 males and 7 females) were included in this descriptive observational study (both qualitative and quantitative). The mean patient age was 55.50 ± 10.21 years (range 27–70 years) and the median was 56.5 years (range 49–63 years). All patients underwent Echo, CAG and PET/CT scan. Chest tightness was the most common symptom in our study. Most patients had normal blood pressure (n = 18, 64.3%) while only (n = 10, 37.5%) had hypertension, and (n = 1, 3.6%) had diabetes mellitus. The mean HDL in CMVD (n = 25) and non-CMVD (n = 3) were 1.30 ± 0.39 and 1.08 ± 0.95, respectively, indicating that the difference between the groups was statistically significant (p = 0.04). Similarly, the mean HBA1c- (glycated haemoglobin) in CMVD (n = 25) and non-CMVD (n = 3) were 5.6 ± 0.53 and 5.0 ± 0.26, respectively, with (p = 0.03). Our findings managed to show the association between biomarkers and PET/CT CFR in confirming the diagnosis of coronary microvascular dysfunction. [ABSTRACT FROM AUTHOR] |
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قاعدة البيانات: |
Complementary Index |