التفاصيل البيبلوغرافية
| العنوان: |
The burden of neovascular age-related macular degeneration: a patient's perspective. |
| المؤلفون: |
Spooner, Kimberly L, Mhlanga, Cleopatra T, Hong, Thomas H, Broadhead, Geoffrey K, Chang, Andrew A |
| المصدر: |
Clinical Ophthalmology; Dec2018, Vol. 12, p2483-2491, 9p |
| مصطلحات موضوعية: |
RETINAL degeneration, MEDICAL care costs, QUALITY of life, VASCULAR endothelial growth factors, DRUG therapy |
| مصطلحات جغرافية: |
AUSTRALIA |
| مستخلص: |
Purpose: To quantify the burden and quality of life of patients and their caregivers in a cohort of patients with neovascular age-related macular degeneration (nAMD) in an Australian clinical setting. Methods: A total of 103 patients undergoing anti-vascular endothelial growth factor (VEGF) therapy for nAMD were asked to complete questionnaires relating to the financial and time burdens of nAMD. Results: All patients completed the questionnaires. Loss in productivity due to attendance of appointments was 4.4±1.7 hours per month, with additional time lost by caregivers. Financial strain was incurred by direct medical costs associated with intravitreal assessment and injections at an average of AU$199.2±$83.1 per month. Indirect costs incurred averaged $64.8±$79.7 per month. Qualitative indirect costs due to loss of productivity for the patient, unpaid caregivers, and loss of productivity due to premature mortality were also a considerable burden. Overall mean Visual Function Questionnaire and EuroQol 5D-3L scores were correlated with visual acuity and demonstrated patients' subjective decline in quality of vision. Conclusion: Management of nAMD carries a substantial burden on patients and caregivers. These results provide important information in understanding the effect of anti-VEGF therapy among patients with nAMD. Together with the quality-of-life burden on the patients, the management of nAMD has a significant societal impact. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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