التفاصيل البيبلوغرافية
| العنوان: |
Incidence and risk of major heart diseases in middleaged adults with moderate to severe vision impairment: a population-based cohort study. |
| المؤلفون: |
Chun-Mei Hsueh, Jing-Hwa Wey, Jong-Shiuan Yeh, Chien-Hua Wu, Tsan-Hon Liou, Kwang-Hwa Chang |
| المصدر: |
British Journal of Ophthalmology; Aug2019, Vol. 103 Issue 8, p1054-1059, 6p, 1 Diagram, 3 Charts, 1 Graph |
| مستخلص: |
Background/aim To estimate the incidence and risk of major adverse cardiovascular events (MACEs), including heart failure and ischaemic heart disease, among middleaged people with a visual disability (VD). Methods We used a national health insurance research database to conduct a population-based cohort study from 1 January 2000 to 31 December 2013. Patients with VD aged 35~65 years were recruited. For each VD patient, five age-matched, sex-matched and comorbiditymatched patients were randomly selected and recruited as controls. Control patients had no documented disability. Results This study recruited 978 patients with VD (mean age±SD, 55.1±7.8 years; 48.9% male) and 4677 controls. Compared with the same sex of the controls, women with VD had higher incidence of MACE 1 (7.9 vs 2.8/1000 person-years, p<0.001), MACE 2 (27.5 vs 16.9/1000 person-years, p<0.001), MACE 3 (3.7 vs 1.4/1000 person-years, p<0.005) and MACE 4 (4.5 vs 2.5/1000 person-years, p<0.05), and men with VD had higher incidence of MACE 1 (4.6 vs 2.0/1000 personyears, p<0.005). Compared with the controls, patients with VD had lower cumulative MACE 1~MACE 4-free probabilities and had an independently higher risk of MACE 1~MACE 4 during the 13-year study, yielding an adjusted hazard ratio range of 1.31~2.75. Those persons with VD who had diabetes and hypertension had greater risks of MACE 1~MACE 4. Conclusions Middle-aged adults with VD were at risk of MACEs. A programme for MACE prevention is important for middle-aged people with VD. This is especially true for women and for those who also have diabetes and hypertension. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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