التفاصيل البيبلوغرافية
| العنوان: |
Fertility outcomes in patients with tubo-ovarian abscesses after an oocyte retrieval: a longitudinal cohort analysis. |
| المؤلفون: |
Fouks, Yuval, Azem, Foad, Many, Ariel, Cohen, Yoni, Levin, Ishai, Cohen, Aviad |
| المصدر: |
Archives of Gynecology & Obstetrics; Sep2019, Vol. 300 Issue 3, p763-769, 7p, 3 Charts |
| مصطلحات موضوعية: |
COHORT analysis, OVARIES, FERTILITY, FERTILIZATION in vitro, ABSCESSES, ABDOMINAL abscess surgery, INFERTILITY treatment, PELVIC inflammatory disease diagnosis, BIRTH rate, FALLOPIAN tube diseases, RETROSPECTIVE studies, EMBRYO transfer, INFERTILITY, OVARIAN diseases, HUMAN artificial insemination, INDUCED ovulation, LONGITUDINAL method, PELVIC inflammatory disease, DISEASE complications |
| مستخلص: |
Purpose: To determine the impact of pelvic inflammation caused by tubo-ovarian abscess (TOA) on ovarian response to stimulation.Methods: This retrospective longitudinal cohort analysis that was carried out in a tertiary university-affiliated medical center included 15 women with TOA during in vitro fertilization (IVF) cycles. The ovarian response to stimulation and the pregnancy rate were compared in two subsequent cycles, the initial IVF cycle that was complicated by TOA after oocyte retrieval (first treatment cycle) and the following IVF treatment (second treatment cycle) that occurred within a period of a year from the first cycle.Results: The mean number of retrieved oocytes was significantly higher in the first IVF cycle compared to the second cycle (8.1 ± 3.2 vs. 5.4 ± 2.5, P = .003], corresponding to a 30% reduction in ovarian response to gonadotropin stimulation. Fertilization rates were significantly lower in the second cycle (4.1 ± 2.9 vs. 2.9 ± 1.7, P = .015). Twelve women (80%) reached embryo transfer in the first cycle compared to 14 women (93.3%) in the second cycle. The mean number of transferred embryos was similar between the two cycles. There were no clinical pregnancies following the first cycle, and only one patient (6.6%) had a clinical pregnancy in the second treatment cycle.Conclusions: TOA following fertility treatment has a detrimental effect on ovarian function. The pregnancy rate in the immediate period following TOA is poor. Current data for recommending the deferral of fertility treatment following a TOA episode are insufficient, calling for more studies to address these issues. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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