التفاصيل البيبلوغرافية
| العنوان: |
Progressive Supranuclear Palsy with Wall-Eyed Bilateral Internuclear Ophthalmoplegia Syndrome: Authors' Second Case. |
| المؤلفون: |
Matsumoto, Hideyuki, Inaba, Tatsurou, Kakumoto, Toshiyuki, Miyano, Ryoji, Uchio, Naohiro, Sakurai, Yasuhisa |
| المصدر: |
Case Reports in Neurology; 2019, Vol. 11 Issue 2, p205-208, 4p |
| مصطلحات موضوعية: |
PROGRESSIVE supranuclear palsy, EYE paralysis, SYNDROMES, MAGNETIC resonance imaging, NEURODEGENERATION |
| مستخلص: |
Wall-eyed bilateral internuclear ophthalmoplegia (WEBINO) syndrome has previously been reported in only 2 patients with progressive supranuclear palsy (PSP). Herein, we report a third case of WEBINO syndrome with PSP. The patient was an 81-year-old man who had experienced gradually increasing gait disturbance and occasional falls since the age of 78 years. At 80 years of age, he presented with cognitive impairment, parkinsonism, and oculomotor abnormalities. The oculomotor abnormalities consisted of vertical gaze palsy and loss of eye convergence. Brain magnetic resonance imaging demonstrated marked atrophy of the midbrain. He was diagnosed with PSP. At the age of 81 years, he presented with alternating extropia in his forward gaze and adduction paresis and outward nystagmus of the abducted eye in his horizontal gaze, both of which were compatible with WEBINO syndrome. Previously, we reported the first case of PSP with WEBINO syndrome, and another group recently reported a second case. In light of the previous cases and the present case, WEBINO syndrome in PSP should not be considered extremely rare. Furthermore, WEBINO syndrome has not been reported in other neurodegenerative disorders, which suggests that it might be a useful and specific diagnostic finding in PSP. [ABSTRACT FROM AUTHOR] |
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