التفاصيل البيبلوغرافية
| العنوان: |
Elevation of Serum Cardiac Troponin I Concentraion in Dogs Experimentally Infected with Trypanosoma Congolense. |
| المؤلفون: |
Abakpa, S. A. V., Talabi, A. O., Oyekunle, M. A., Ajibola, E. S., Adebiyi, A. A., Mshelbwala, F. M., Akintunde, G. O., Daramola, O. O., Adeleye, O. E., Okandeji, M. E. |
| المصدر: |
Alexandria Journal of Veterinary Sciences; 2020, Vol. 64 Issue 1, p123-128, 6p |
| مصطلحات موضوعية: |
TROPONIN I, VETERINARY protozoology, TRYPANOSOMA, DOG breeds, DOGS, BEAGLE (Dog breed), DOG breeding, CANIDAE |
| مصطلحات جغرافية: |
AFRICA |
| مستخلص: |
Animal African Trypanosomosis (AAT) is a devastating protozoan disease of animals and humans caused by Trypanosoma spp resulting in a great economic loss in the livestock industries, in the sub-sahara Africa. Cardiac troponin I is released from myocytes in both reversible and irreversible myocardial injuries. This study investigated the expression of cardiac troponin I (cTn I) in dogs experimentally infected with Trypanosoma congolense. Fifteen mongrel dogs of both sexes and with average body weights of 9.3 kg were divided into three groups (A, B and C). Dogs in group A were uninfected, group B were infected but untreated, while group C were infected and treated with Diminazene aceturate at a single dose of 3.5 mg/kg intramuscularly. The serum cTn I concentrations in infected dogs were elevated on days 1, 10 and 17 post-infection (pi). Serum cTn I concentrations in dogs that were infected and treated decreased on day 5 post-treatment (day 22 pi) compared to those that were infected but not treated. Post mortem and histopathological findings in the heart of a dogs that died of the disease in the infected but not treated group revealed no visible lesions. We concluded that the elevation of cTn I in Mongrel breed of dogs can occur without structural damage to cardiac muscles. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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