التفاصيل البيبلوغرافية
| العنوان: |
Bivalent Vaccine Effectiveness Against Anal Human Papillomavirus Positivity Among Female Sexually Transmitted Infection Clinic Visitors in the Netherlands. |
| المؤلفون: |
Woestenberg, Petra J, King, Audrey J, Benthem, Birgit H B Van, Leussink, Suzan, Sande, Marianne A B Van der, Hoebe, Christian J P A, Bogaards, Johannes A, Services, Medical Microbiological Laboratories and the Public Health, Van Benthem, Birgit H B, Van der Sande, Marianne A B, Medical Microbiological Laboratories and the Public Health Services |
| المصدر: |
Journal of Infectious Diseases; 4/15/2020, Vol. 221 Issue 8, p1280-1285, 6p |
| مصطلحات موضوعية: |
VACCINE effectiveness, SEXUALLY transmitted diseases, ANAL cancer, PAPILLOMAVIRUSES, ANUS, COMPARATIVE studies, FEMALE reproductive organ diseases, IMMUNITY, IMMUNIZATION, RESEARCH methodology, MEDICAL cooperation, PAPILLOMAVIRUS diseases, RESEARCH, COMBINED vaccines, HUMAN papillomavirus vaccines, EVALUATION research, CROSS-sectional method |
| مصطلحات جغرافية: |
NETHERLANDS |
| مستخلص: |
Human papillomavirus (HPV) vaccines are indicated for anal cancer prevention, but evidence for vaccine effectiveness (VE) against anal HPV infections among women is limited. We estimated the VE (≥1 dose) against anal HPV positivity of the bivalent vaccine, whose target types HPV-16/18 are associated with approximately 90% of HPV-related anal cancers. Among 548 female STI clinic visitors 16-24 years old who provided an anal swab sample as part of a repeated cross-sectional survey, VE against HPV-16/18 was 89.9% (95% confidence interval, 63.0%-97.2%). Type-specific VE correlated well with VE against cervicovaginal HPV (Spearman ρ = 0.76), suggesting comparable effectiveness of HPV-16/18 vaccination against genital and anal infections. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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