دورية أكاديمية

Prevalence of hepatitis B and hepatitis C viral infections and impact of control program among blood donors in Al-Baha region, Saudi Arabia.

التفاصيل البيبلوغرافية
العنوان: Prevalence of hepatitis B and hepatitis C viral infections and impact of control program among blood donors in Al-Baha region, Saudi Arabia.
المؤلفون: Sallam, Talal, El-Bingawi, Haitham, Alzahrani, Khalid, Alzahrani, Bader, Alzahrani, Atyah
المصدر: Saudi Journal for Health Sciences; Jan-Apr2020, Vol. 9 Issue 1, p56-60, 5p
مصطلحات موضوعية: VIRUS diseases, BLOOD donors, MIDDLE East respiratory syndrome, HEPATITIS B, HEPATITIS C virus, HEPATITIS B virus, VIRAL hepatitis
مصطلحات جغرافية: SAUDI Arabia
مستخلص: Background: A low prevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections has been previously reported in Al-Baha. The present study reexamines the prevalence of HBV and HCV infection among blood donors 3 years following a previous study in an attempt to detect an impact of control measures. Materials and Methods: This 29-month retrospective study was conducted from October 2014 to May 2017. A total of 3,461 blood donors were screened for serological and molecular markers for HBV and HCV. Results: The mean age of the donors was 32.4 ± 10. 1 (range: 17–67). Of all donors 10 (0.3%) had HBsAg while 253 (7.3%) had anti-HBc in absence of HBsAg. Anti-HCV was detected in 8 (0.2%) donors, of whom 6 (75.0%) were also HCV-RNA positive. HBV-DNA was detected in 12 (0.4%) donors, of whom 10 (83.3%) had concurrent HBsAg, whereas 2 (16.7%) had HBV-DNA with anti-HBc as the only HBV marker. The donors born after inclusion of HBV vaccine in expanded program of immunization (EPI) had a significantly (P < 0.05) lower prevalence of HBsAg, anti-HBc, and HBV-DNA. Although insignificant (P = 0.197), a lower prevalence of HCV infection was detected among the donors who were born after implementing the screening policy for HCV infection. Conclusion: Compared to a previous report, this study detected a further reduction in the prevalence of HBV, whereas the decline of the prevalence of HCV infection merits further investigation. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:22781900
DOI:10.4103/sjhs.sjhs_197_19