دورية أكاديمية

Frequency and prognosis of metastasis to liver, lung, bone and brain from Merkel cell carcinoma.

التفاصيل البيبلوغرافية
العنوان: Frequency and prognosis of metastasis to liver, lung, bone and brain from Merkel cell carcinoma.
المؤلفون: Xia, Yi-Jun, Cao, Dong-Sheng, Zhao, Jun, Zhu, Bang-Zhong, Xie, Juan
المصدر: Future Oncology; Jun2020, Vol. 16 Issue 16, p1101-1113, 13p
مستخلص: Aim: To describe the factors affecting distant metastasis of Merkel cell carcinoma (MCC) and the prognosis of metastatic MCC. Materials & methods: The MCC patient information was downloaded from the SEER database. Logistic regression and Cox proportional hazard models were conducted to screen for significant factors. Results: A total of 3449 patients were enrolled. Surgery and chemotherapy were significantly correlated with the occurrence of distant metastasis. In the cause-specific survival rate of MCC, regional lymph node removal, sentinel lymph node biopsy, radiation and chemotherapy can significantly reduce the prognostic risk of patients with distant metastases. Conclusion: Our study screened out the factors affecting the distant metastasis and prognosis of MCC and more prospective studies are needed to verify our findings. [ABSTRACT FROM AUTHOR]
Copyright of Future Oncology is the property of Future Medicine Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
قاعدة البيانات: Complementary Index
الوصف
تدمد:14796694
DOI:10.2217/fon-2020-0064