التفاصيل البيبلوغرافية
| العنوان: |
The epidemiology of cryptosporidiosis in Ontario, Canada following the introduction of PCR testing in 2018. |
| المؤلفون: |
Johnson, Karen, Thayani, Palvasha, Warshawsky1, Bryna, Whitfield, Yvonne, Pritchard, Jennifer, Murti, Michelle |
| المصدر: |
Canada Communicable Disease Report; Jul2020, Vol. 46 Issue 7/8, p227-230, 4p |
| مصطلحات موضوعية: |
POLYMERASE chain reaction, CRYPTOSPORIDIOSIS, EPIDEMIOLOGY |
| مصطلحات جغرافية: |
ONTARIO |
| مستخلص: |
Background: Cryptosporidiosis is reportable in Ontario, Canada. Detection by polymerase chain reaction (PCR) was introduced by a large community-based laboratory in August 2017, and in 2018, the incidence of reported cryptosporidiosis doubled compared to 2012–2016. Methods: We assessed cases reported in 2018 for epidemiologic changes since the introduction of PCR testing. Results: No outbreaks were identified in 2018, and 48% of cases were detected by PCR, suggesting that the observed increase was likely the result of PCR's higher sensitivity compared with previous detection method. From the pre to post-PCR periods, the proportion of female cases increased significantly, due mainly to cases diagnosed by PCR. A significant increase in mean age was also observed among cases diagnosed by microscopy and/or PCR in the post- PCR period. Conclusion: Our findings highlight the importance of assessing diagnostic methods when evaluating changes in reported rates. The observed changes in incidence will require ongoing monitoring and may require shorter baseline periods for aberration detection. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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