التفاصيل البيبلوغرافية
| العنوان: |
PENFIGÓIDE BOLHOSO INDUZIDO POR FÁRMACO: UM RELATO DE CASO. (Portuguese) |
| Alternate Title: |
DRUG-INDUCED BULLOUS PEMPHIGOID: A CASE REPORT. (English) |
| المؤلفون: |
Lonchiati, Danielle F., de Oliveira, Beatriz S., Silva, Andressa L. F., Souza, Beatrice S., Carapeba, Murilo O., Pivaro, Luíza R., Kerche, Leandra E. |
| المصدر: |
Colloquium Vitae; 2020, Vol. 12 Issue 2, p6-11, 6p |
| مصطلحات موضوعية: |
BULLOUS pemphigoid, DRUG side effects, ETIOLOGY of diseases, URBAN hospitals, QUINOLONE antibacterial agents |
| Abstract (English): |
Bullous pemphigoid is the most common autoimmune dermatosis that can be caused by drugs. The objective of this study was following the evolution of a patient with pharmacodermia in use of several drugs. A female patient was treated in a hospital in the city of Presidente Prudente, presenting intact and broken blisters, require etiological investigation. Other diagnostic hypotheses such as porphyria cutanea tarda were ruled out, and the diagnosis of bullous pemphigoid of pharmacological etiology was suggested through cutaneous biopsy of a blister. We stopped using antibiotics and kept the medication in continuous use. It was introduced oral prednisone and topical dexamethasone, and it was possible to observe a favorable evolution of the condition, without intercurrences and reduction of the blisters until only residual lesions remained. By analyzing the variables of the case it is assumed that the quinolones were responsible for the condition, emphasizing the importance of knowing the drug reactions to guarantee an early diagnosis. [ABSTRACT FROM AUTHOR] |
| Abstract (Portuguese): |
O penfigóide bolhoso é a mais comum dermatose autoimune podendo ser desencadeada por fármacos. O objetivo desse estudo foi acompanhar a evolução de uma paciente com farmacodermia em uso de diversos medicamentos. Paciente do sexo feminino foi atendida em um hospital na cidade de Presidente Prudente, apresentando bolhas íntegras e rotas, necessitando de investigação etiológica. Foram descartadas outras hipóteses diagnósticas como porfiria cutânea tarda e através da biópsia cutânea de uma bolha foi sugerido o diagnóstico de penfigóide bolhoso de etiologia farmacológica. Suspendemos o uso de antibióticos e mantivemos a medicação de uso contínuo. Foi introduzida prednisona oral e dexametasona tópico, podendo observar evolução favorável do quadro, sem intercorrências, com diminuição das bolhas até restar apenas lesões residuais. A análise das variáveis do caso permitiu pressupor que as quinolonas foram as responsáveis pelo quadro, ressaltando a importância de conhecer as reações medicamentosas para garantir um diagnóstico precoce. [ABSTRACT FROM AUTHOR] |
|
Copyright of Colloquium Vitae is the property of Asociacao Prudentina de Educacao e Cultura (APEC) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
Full Text Finder