التفاصيل البيبلوغرافية
| العنوان: |
Attributes and risk factors of positive margins on 864 excisions of basal cell carcinomas: a single-center retrospective study. |
| المؤلفون: |
Filho, Roberto Bueno, de Carvalho Fantini, Bruno, dos Santos, Cecília Anatriello, Melo, Rafael V. G., Rosan, Isadora, Chahud, Fernando, da Silva Souza, Cacilda |
| المصدر: |
Journal of Dermatological Treatment; Sep2020, Vol. 31 Issue 6, p589-596, 8p |
| مصطلحات موضوعية: |
BASAL cell carcinoma, SURGICAL excision, SURGICAL site, RETROSPECTIVE studies, UNIVERSITY hospitals |
| مستخلص: |
Background: Residual tumors increase the likelihood of recurrence of basal cell carcinoma (BCC). Objective: We determined the attributes and risk factors for positive surgical margins (+SM) of excised BCC in a university hospital. Methods: In this cross-sectional retrospective study, we reviewed the histologic reports of BCC removed via conventional surgical excision (CSE) by specialists from different fields. Results: Among excised BCCs (n = 864), there was a predominance of nodular BCC (82.64%) in the facial H-area (72.81%; average diameter = 9.12 mm), which had the highest + SM rate (20.17%). Most cephalic (ce-BCC; 69.01%) and non-cephalic (91.11%) BCCs were excised by dermatologists, with low rates of + SM (4.53%; 1.46%, respectively); the overall + SM rate was 12.73%. Men had larger (p <.001) and more ulcerated (p =.04) BCC. An aggressive histologic pattern (Ag-P) (p <.04) and ulceration (p <.001) were correlated with tumor size on multivariate analysis. The risk for + SM increased in ulcerated ce-BCC (p =.02), BCC with Ag-P (p =.02), and in the H-area (p <.001), nasal (p =.007), and labial (p =.05) regions. ce-BCC excised by head-neck surgeons had a high chance of ulceration (p <.001) and Ag-P (p =.002). Conclusions: Ag-P and H-zone remain critical risk factors for + SM. Accordingly appropriate treatment protocols should be used to ensure low + SM rates via CSE. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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