التفاصيل البيبلوغرافية
| العنوان: |
Bacteriological Assessment, Antibiogram, And Factors Related To Positivity Of Bile Culture In Cholelithiasis. |
| المؤلفون: |
Alif, Yunus Mohammad, Sani, Mohamad Ikhwan, Ziyadi, Ghazali Mohd, Anwar, Abdul Rahman Khairul, Azri, Iskandar, Hartinie, Mohamad Siti, Norhaslina, Abdullah Fatimah, Norlela, Othman |
| المصدر: |
Surgical Chronicles; Jul-Sep2020, Vol. 25 Issue 3, p240-245, 6p |
| مصطلحات موضوعية: |
CHOLECYSTECTOMY, BACTERIOLOGY, ANTIBIOTICS, LAPAROSCOPIC surgery, DRUG resistance in bacteria |
| مستخلص: |
Background: Cholecystitis is one of the most common surgical diseases, and effective empirical antibiotic therapy is essential in the treatment of acute cholecystitis. Objective: To determine the bacteriological analysis, antibiotic sensitivity and resistance pattern of bile culture from laparoscopic cholecystectomy patient. Method: This cross-sectional study was conducted from July 2017 to March 2018 in Hospital Sultanah Nurzahirah, Kuala Terengganu, Malaysia. Bile sample was taken intra-operatively from a number of 62 patients who underwent elective uncomplicated laparoscopic cholecystectomy for cholelithiaisis. The samples were sent for bacteriological assessment and antibiotic sensitivity testing. The factors affecting the positivity of bile culture was age, diabetic, obesity, previous treatment of antibiotics and prophylaxis antibiotics. Results: The prevalence for positive bile culture in the study was 19%. There was no anaerobic bacteria detected, Klebsiella Pneumonia was the commonest organism isolated which were 9 out of 12 samples (75%), compared to Escherechia coli which were 8 out of 12 samples (66.67%). From the antibiogram, it showed cefuroxime has the highest number of antibiotic sensitivity tested (11 out of 12), followed by gentamicin (9 out of 12) and ciprofloxacin (7 out of 12). There were 6 samples with ampicillin resistance, and 1 sample with cefuroxime resistance. From Multiple Logistic Regression analysis, with every 1 year increment of age, there is 1.10 higher odds of having positive bile culture when other variables are adjusted (p = 0.017). Those who have previous antibiotic treatment will have 7.98 higher odds of having positive bile culture when other variables are adjusted (p=0.035). Conclusion: The prevalence of positive bile culture sample in uncomplicated laparoscopic cholecystectomy is high (19%). The antibiotic treatment practice need to be improvised as the data shows patient with previous antibiotic treatment has 7.98 higher odds of having positive bile culture. [ABSTRACT FROM AUTHOR] |
|
Copyright of Surgical Chronicles is the property of Surgical Society of Northern Greece and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
