دورية أكاديمية

Effective methylation triage of HPV positive women with abnormal cytology in a middle‐income country.

التفاصيل البيبلوغرافية
العنوان: Effective methylation triage of HPV positive women with abnormal cytology in a middle‐income country.
المؤلفون: Ramírez, Arianis Tatiana, Sánchez, Gloria Inés, Nedjai, Belinda, Agudelo, María Cecilia, Brentnall, Adam R., Cuschieri, Kate, Castañeda, Kelly Melisa, Cuzick, Jack, Lorincz, Attila T., Sanchez (PI), Gloria I, Baena, Armando, Agudelo, Maria C, Tatiana Ramirez, Arianis, Melisa Castañeda, Kelly, Borrero, Mauricio, Riveros, Marcela, Bedoya, Astrid, Botero, Alejandra, Villa, Catalina, Florez, Victor
المصدر: International Journal of Cancer; Mar2021, Vol. 148 Issue 6, p1383-1393, 11p
مصطلحات موضوعية: MIDDLE-income countries, CYTOLOGY, CERVICAL intraepithelial neoplasia, METHYLATION, MEDICAL triage
مستخلص: The S5‐methylation test, an alternative to cytology and HPV16/18 genotyping to triage high‐risk HPV‐positive (hrHPV+) women, has not been widely validated in low‐middle‐income countries (LMICs). We compared S5 to HPV16/18 and cytology to detect cervical intraepithelial neoplasia Grade 2 or worse (CIN2+) and CIN3+ in hrHPV+ women selected from a randomized pragmatic trial of 2661 Colombian women with an earlier‐borderline abnormal cytology. We included all hrHPV+ CIN2 and CIN3+ cases (n = 183) age matched to 183
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قاعدة البيانات: Complementary Index
الوصف
تدمد:00207136
DOI:10.1002/ijc.33314