دورية أكاديمية

MC1R variants in relation to naevi in melanoma cases and controls: a pooled analysis from the M‐SKIP project.

التفاصيل البيبلوغرافية
العنوان: MC1R variants in relation to naevi in melanoma cases and controls: a pooled analysis from the M‐SKIP project.
المؤلفون: Stefanaki, I., Stratigos, A.J., Kypreou, K.P., Evangelou, E., Gandini, S., Maisonneuve, P., Polsky, D., Lazovich, D., Newton‐Bishop, J., Kanetsky, P.A., Puig, S., Gruis, N.A., Ghiorzo, P., Pellegrini, C., De Nicolo, A., Ribas, G., Guida, G., Garcia‐Borron, J.C., Fargnoli, M.C., Nan, H.
المصدر: Journal of the European Academy of Dermatology & Venereology; Feb2021, Vol. 35 Issue 2, pe135-e138, 4p
مصطلحات موضوعية: MELANOMA, DYSPLASTIC nevus syndrome, MELANOCORTIN receptors, BIOLOGICAL pigments, SKIN cancer
مستخلص: MC1R variants in relation to naevi in melanoma cases and controls: a pooled analysis from the M-SKIP project There have been a limited number of studies exploring the possible influence of I MC1R i variants in naevi formation and/or their interaction with naevi in melanoma development. Our results are in agreement with the notion that I MC1R i is not implicated in naevogenesis, but also imply that it may act as a modifier of melanoma risk in individuals with atypical naevi by enhancing their risk to develop melanoma. [Extracted from the article]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:09269959
DOI:10.1111/jdv.16869