التفاصيل البيبلوغرافية
العنوان: |
Oxidative‐Species‐Selective Materials for Diagnostic and Therapeutic Applications. |
المؤلفون: |
Zhao, Caiyan, Chen, Jingxiao, Zhong, Ruibo, Chen, Dean Shuailin, Shi, Jinjun, Song, Jibin |
المصدر: |
Angewandte Chemie International Edition; 4/26/2021, Vol. 60 Issue 18, p9804-9827, 24p |
مصطلحات موضوعية: |
OXIDATIVE stress |
مستخلص: |
With the increasing recognition of the diverse roles and significance of oxidative species in the pathogenesis of many diseases, a tremendous amount of work on the development of oxidative‐species‐responsive materials has been conducted for 1) detecting oxygen metabolites or diagnosis of oxidative‐stress‐relevant diseases, 2) reducing oxidative stress in the disease sites, and/or 3) delivering therapeutic and diagnostic agents. In this review, we first discuss the distinct features and biological functions of each oxidative species. Then the selectivity and sensitivity of chemical linkers/groups to specific oxidative species and the underlying chemistry of their particular interactions are systematically elucidated. Their potential biomedical applications are also highlighted. We expect that this comprehensive review will provide more insights for the design and development of oxidative‐species‐selective materials for more effective diagnostic and therapeutic applications. [ABSTRACT FROM AUTHOR] |
|
Copyright of Angewandte Chemie International Edition is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
قاعدة البيانات: |
Complementary Index |