التفاصيل البيبلوغرافية
| العنوان: |
The Vitreous Ecosystem in Diabetic Retinopathy: Insight into the Patho-Mechanisms of Disease. |
| المؤلفون: |
Iyer, Siva S.R., Lagrew, Mollie K., Tillit, Stephanie M., Roohipourmoallai, Ramak, Korntner, Samuel |
| المصدر: |
International Journal of Molecular Sciences; Jul2021, Vol. 22 Issue 13, p7142-7142, 1p |
| مصطلحات موضوعية: |
DIABETIC retinopathy, VITREOUS humor, GROWTH factors, CYTOKINES, DISEASE incidence |
| مستخلص: |
Diabetic retinopathy is one of the leading causes of blindness in the world with the incidence of disease ever-increasing worldwide. The vitreous humor represents an extensive and complex interactive arena for cytokines in the diabetic eye. In recent decades, there has been significant progress in understanding this environment and its implications in disease pathophysiology. In this review, we investigate the vitreous ecosystem in diabetic retinopathy at the molecular level. Areas of concentration include: the current level of knowledge of growth factors, cytokine and chemokine mediators, and lipid-derived metabolites in the vitreous. We discuss the molecular patho-mechanisms of diabetic retinopathy based upon current vitreous research. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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