التفاصيل البيبلوغرافية
| العنوان: |
Paratrabecular bone marrow involvement in autoimmune lymphoproliferative syndrome: a potential diagnostic pitfall as a lymphoma mimic. |
| المؤلفون: |
Raine, Juliet I., Dowse, Robin, Attygalle, Ayoma D. |
| المصدر: |
Histopathology; Mar2022, Vol. 80 Issue 4, p740-742, 3p |
| مصطلحات موضوعية: |
LYMPHOPROLIFERATIVE disorders, BONE marrow, LYMPHOMAS, T cells, ANAPLASTIC large-cell lymphoma, T-cell lymphoma, RITUXIMAB, CD30 antigen |
| مستخلص: |
Six years after diagnosis, the patient underwent bone marrow (BM) trephine biopsy to investigate worsening cytopaenias. However, a variety of lymphomas have been reported, including T-cell lymphoma and T-cell histiocyte-rich large B-cell lymphoma.2 In essence, a lymphoma rich in T cells is quite feasible in an ALPS patient. In our case, there was down-regulation of CD7, which is a feature that may be observed in some normal and reactive T cells, and has been reported in the double-negative T cells in ALPS.7 The distribution of a lymphoid infiltrate within BM is a recognised diagnostic clue to the underlying aetiology. [Extracted from the article] |
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