التفاصيل البيبلوغرافية
| العنوان: |
Exposure to inorganic particles in paediatric sarcoidosis: the PEDIASARC study. |
| المؤلفون: |
Nathan, Nadia, Montagne, Marie-Emeline, Macchi, Odile, Rosental, Paul-André, Chauveau, Simon, Jeny, Florence, Sesé, Lucile, Taam, Rola Abou, Brocvielle, Manon, Brouard, Jacques, Catinon, Mickaël, Chapelon-Abric, Catherine, Cohen-Aubart, Fleur, Delacourt, Christophe, Delestrain, Céline, Deschildre, Antoine, Dossier, Antoine, Epaud, Ralph, Haroche, Julien, Houdouin, Véronique |
| المصدر: |
Thorax; Apr2022, Vol. 77 Issue 4, p404-407, 4p |
| مصطلحات موضوعية: |
SARCOIDOSIS, PEDIATRICS, MINERAL dusts, RESEARCH, DUST, RESEARCH methodology, OCCUPATIONAL exposure, EVALUATION research, TALC, OCCUPATIONS, COMPARATIVE studies, ENVIRONMENTAL exposure |
| مستخلص: |
Inorganic antigens may contribute to paediatric sarcoidosis. Thirty-six patients matched with 36 healthy controls as well as a group of 21 sickle-cell disease (SCD) controls answered an environmental questionnaire. Patients' indirect exposure to inorganic particles, through coresidents' occupations, was higher than in healthy and SCD controls (median score: 2.5 (0.5-7) vs 0.5 (0-2), p=0.003 and 1 (0-2), p=0.012, respectively), especially for construction, exposures to metal dust, talc, abrasive reagents and scouring products. Wood or fossil energies heating were also linked to paediatric sarcoidosis. This study supports a link between mineral environmental exposure due to adult coresident occupations and paediatric sarcoidosis. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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