التفاصيل البيبلوغرافية
العنوان: |
Human malignant melanoma. |
المؤلفون: |
Hunter, J. A. A., Paterson, W. D., Fairley, D. J. |
المصدر: |
British Journal of Dermatology; Apr1978, Vol. 98 Issue 4, p381-390, 10p |
مصطلحات موضوعية: |
TUMORS, MELANOMA, CANCER cells, NEUROENDOCRINE tumors, ONCOLOGY, CELLS |
مستخلص: |
An ultrastructural dopa reaction, with glutaraldehydeaformaldehyde prefixation, was carried out on ten specimens of malignant melanoma showing a wide variation in melanosomal morphology. All tumours, but only a minority of tumour cells, contained reaction product. In all tumours the reaction product was distributed similarly in the Golgi apparatus and Golgi associated endoplasmic reticulum (GERL). However, differences were noted in its deposition in melanosomes. Whereas vacuolar and lamellar profiles sometimes contained reaction product, it was not seen in normal, granwar and abortive melanosomes. Tumour cells without metanosomes were also seen to contain reaction product. [ABSTRACT FROM AUTHOR] |
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قاعدة البيانات: |
Complementary Index |