التفاصيل البيبلوغرافية
| العنوان: |
Enrichment of rare variants of BIN1 but not APOE genes in Chinese patients with Parkinson's disease. |
| المؤلفون: |
Li, Chun Yu, Ou, Ru Wei, Chen, Yong Ping, Gu, Xiao Jing, Wei, Qian Qian, Hou, Yan Bing, Cao, Bei, Zhang, Ling Yu, Lin, Jun Yu, Liu, Kun Cheng, Song, Wei, Zhao, Bi, Wu, Ying, Shang, Hui Fang |
| المصدر: |
Journal of Internal Medicine; May2022, Vol. 291 Issue 5, p698-701, 4p |
| مصطلحات موضوعية: |
PARKINSON'S disease, CHINESE people, LEWY body dementia, MOVEMENT disorders |
| مستخلص: |
Considering that I GBA i , I TMEM175 i , and I SNCA i are risk genes for both LBD and PD, it is noteworthy to investigate whether I BIN1 i and I APOE i are also associated with the risk of PD. Keywords: APOE; BIN1; Parkinson's disease; rare variant EN APOE BIN1 Parkinson's disease rare variant 698 701 4 04/15/22 20220501 NES 220501 Abbreviations GWAS genome-wide association study LBD Lewy body dementia PD Parkinson's disease Dear Editor, Recently, Chia et al. identified five risk genes for Lewy body dementia (LBD) in a genome-wide association study (GWAS) [1]. Similarly, a previous study identified that the I BIN1 i variant rs13403026 was associated with later AAO in I GBA i -associated PD [4], suggesting the potential role of I BIN1 i in regulating AAO in PD. [Extracted from the article] |
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| قاعدة البيانات: |
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