التفاصيل البيبلوغرافية
| العنوان: |
Smjernice Hrvatskog društva za transfuzijsku medicinu za određivanje Rh(D) krvne grupe i primjenu RhD genotipizacije. (Croatian) |
| Alternate Title: |
Guidelines of the Croatian Society for Transfusion Medicine for determination of Rh (D) blood group and application of RhD genotyping. (English) |
| المؤلفون: |
Galić, Zrinka Kruhonja, Raos, Mirela, Bošnjak, Bojana, Dajak, Slavica, Caser, Linda, Bingulac-Popović, Jasna, Hećimović, Ana, Jagnjić, Sandra, Đogić, Vesna, Jukić, Irena |
| المصدر: |
Lijecnicki Vjesnik; 2022, Vol. 144 Issue 5/6, p125-133, 9p |
| مصطلحات موضوعية: |
ERYTHROBLASTOSIS fetalis, BLOOD transfusion, PREGNANT women, EMERGENCY medicine, BLOOD group antigens, BLOOD grouping & crossmatching, BLOOD groups |
| Abstract (English): |
The working group of the Croatian Society for Transfusion Medicine has prepared guidelines for the determination of Rh (D) blood group and the application of RhD genotyping. The guidelines describe clinical significance of D antigen, history and limitations of serological testing for D antigen, and possibility of RhD genotyping. The aim of the guidelines is to publish new procedures for serological determination of Rh (D) blood groups in patients, pregnant women and newborns with instructions for transfusion medicine specialists in emergency and regular work, and interpretations of findings for gynecologists, pediatricians, neonatologists, anesthesiologists, internists, and physicians who in their work meet patients who receive blood products and decide on the use of RhIG immunoprophylaxis. As a result of implementation of the guidelines, monitoring and periodic reporting in case of suspicion of RhD immunization in a person carrying the D variant is envisaged. During pregnancy there is a possibility of non-invasive determination of prenatal fetal RhD genotype from maternal plasma after the 16th week of gestation, as an important tool in assessing the risk of developing hemolytic disease of the fetus and newborn. For ease of reference, the types of blood sampling containers and the required quantity of samples are listed. This test is available at the Croatian Institute of Transfusion Medicine at the request of a gynecologist and is recommended primarily to RhD immunized pregnant women, and in case of decisions on early prenatal anti-D immunoprophylaxis for all Rh (D) negative non-immunized pregnant women. [ABSTRACT FROM AUTHOR] |
| Abstract (Croatian): |
Radna skupina Hrvatskog društva za transfuzijsku medicinu pripremila je smjernice za određivanje Rh(D) krvne grupe i primjenu RhD genotipizacije. U smjernicama je opisan klinički značaj antigena D, povijest i ograničenja serološkog testiranja antigena D te mogućnosti RhD genotipizacije. Cilj smjernica bio je objava novih postupnika serološkog određivanja Rh(D) krvne grupe bolesnicima, trudnicama i novorođenčadi s uputama za specijaliste transfuzijske medicine u hitnom i redovnom radu te tumačenjima nalaza namijenjenim ginekolozima, pedijatrima, neonatolozima, anesteziolozima, internistima, liječnicima obiteljske medicine te svim liječnicima koji se u svom radu susreću s bolesnicima koji primaju krvne pripravke i donose odluku o primjeni RhIG imunoprofilakse. Kao rezultat provođenja smjernica predviđeno je praćenje i periodično izvještavanje u slučaju sumnje na RhD imunizaciju kod osoba nositelja D-varijante. Tijekom trudnoće postoji i mogućnost neinvazivnog određivanja prijenatalnog fetalnog RhD genotipa iz majčine plazme iza 16. tjedna gestacije, kao važnog alata u procjeni rizika razvoja hemolitičke bolesti fetusa i novorođenčeta. Radi lakšeg snalaženja navedene su vrste spremnika za uzorkovanje krvi i potrebna količina uzoraka. Navedena pretraga dostupna je u Hrvatskom zavodu za transfuzijsku medicinu na zahtjev ginekologa, a preporučuje se prvenstveno RhD imuniziranim trudnicama te u slučaju donošenja odluke o ranoj prijenatalnoj anti-D imunoprofilaksi i svim Rh(D) negativnim neimuniziranim trudnicama. [ABSTRACT FROM AUTHOR] |
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