دورية أكاديمية

The Importance of Osmolarity in the Prognosis Prediction of ST-elevation and Depression in aVR Derivation of Patients with Acute Coronary Syndrome.

التفاصيل البيبلوغرافية
العنوان: The Importance of Osmolarity in the Prognosis Prediction of ST-elevation and Depression in aVR Derivation of Patients with Acute Coronary Syndrome.
Alternate Title: Akut Koroner Sendrom Hastalarının aVR Derivasyonunda ST-elevasyonu ve Depresyonunun Prognoz Öngörüsünde Osmolaritenin Önemi. (Turkish)
المؤلفون: COŞKUN, Abuzer, HINCAL, Şakir Ömür, EREN, Şevki Hakan
المصدر: Bezmialem Science; 2022, Vol. 10 Issue 3, p281-289, 9p
مصطلحات موضوعية: MYOCARDIAL infarction, ACUTE coronary syndrome, CHEST pain, OSMOLAR concentration, ANGINA pectoris, CORONARY artery disease, PROGNOSIS
Abstract (English): Objective: ST-elevation and depression in augmented voltage right (aVR) are associated with high mortality and prolonged coronary artery disease in patients with the acute coronary syndrome. It was aimed to compare the patients in terms of cardiac troponin, threevessel disease, serum osmolarity and mortality. Methods: The study was performed through retrospective scanning of the files of 372 (162 females, mean age 64±10 years) patients who were admitted to the emergency department due to chest pain between January 2014 and December 2016 and who were admitted to the cardiology clinic with the diagnosis of the acute coronary syndrome. Patients with ST-elevation in aVR were included in Group I and patients with ST-depression in aVR were included in Group II. Results: Osmolarity was 295.8±16 in Group I and 291.7±8.1 in Group II. Troponin values in Group I was higher than Group II (p=0.002). The Gensini score was 40±2.7 in Group I and 28.6±2.3 in Group II (p=0.001). In Group I, unstable angina was found in 32 (18.1%) patient, ST-elevated myocardial infarction (MI) in 135 (76.3%) and non-ST-elevated MI in 10 (5.6%), whereas these numbers and percentages were 62 (31.8%), 106 (54.4%) and 27 (13.8%) in Group II, respectively (p=0.001). The three-vessel disease was found in 56 (31.6%) patients in Group I and 29 (14.9%) patients in Group II (p=0.001). The most common complication in both groups was ischemic heart failure. Mortality was observed in 36 (20.3%) patients in Group I and 14 (7.2%) in Group II. Osmolarity was lowest in unstable angina, highest in non-ST-elevation MI, and was also higher in three-vessel disease, men, and patients with mortality. Conclusion: In patients with acute coronary syndrome, osmolarity may predict ST-elevation and depression in aVR, three-vessel disease, and mortality. [ABSTRACT FROM AUTHOR]
Abstract (Turkish): Amaç: Augmented voltage right'daki (aVR) ST-elevasyonu ve depresyonu akut koroner sendrom hastalarında yüksek mortalite ve uzamış koroner arter hastalığıyla ilişkilidir. Hastaların, kardiyak troponin, üç damar hastalığı, serum osmolarite ve mortalite açısından karşılaştırılması amaçlanmıştır. Yöntemler: Çalışmaya Ocak 2014-Aralık 2016 tarihleri arasında acil servise göğüs ağrısı nedeniyle başvuran, akut koroner sendrom tanısıyla kardiyoloji kliniğine yatırılan, 372 (162 kadın, yaş ortalaması 64±10 yıl) hastanın dosyası retrospektif olarak taranarak dahil edildi. aVR'de ST-elevasyonu olan hastalar Grup 1 ve ST-depresyonu olan hastalar Grup 2 olarak ayrıldı. Hastaların prognozu, yaş, cinsiyet, lipid profili ve Gensini skoru, osmolarite ve mortalite açısından karşılaştırıldı. Bulgular: Grup 1'de osmolarite 295,8±16, Grup 2'de 291,7±8,1 idi (p=0,003). Grup 1'in troponin değerleri Grup 2'den yüksekti. Gensini skoru Grup 1'de 40±2,7, Grup 2'de 28,6±2,3 idi (p=0,001). Grup 1'de unstabil angina 32 (%18,1), ST-elevasyonlu miyokard infarktüsü (MI) 135 (%76,3) ve non-ST-elevasyonlu MI 10 (%5,6) hastada görülürken; Grup 2'de sırasıyla; 62 (%31,8), 106 (%54,4) ve 27(138) hastada görüldü (p=0,001). Üç damar hastalığı Grup 1'de 56 (%31,6), Grup 2'de 29 (%14,9) hastada tespit edildi (p=0,001). Her iki grupta en sık komplikasyon iskemik kalp yetmezliğiydi. Mortalite Grup 1'de 36 (%20,3) ve Grup 2'de 14 (%7,2) hastada görüldü. Osmolarite en düşük unstabil anginada, en yüksek non-ST-elevasyonlu MI'da tespit edildi ve ayrıca üç damar hastalığında, erkeklerde ve mortal seyreden hastalarda yüksek bulundu. Sonuç: Akut koroner sendrom hastalarında osmolarite; aVR'de STelevasyonu ve depresyonu, üç damar hastalığı ve mortalite açısından öngörücü bir değer olabilir. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:21482373
DOI:10.14235/bas.galenos.2021.6212