التفاصيل البيبلوغرافية
| العنوان: |
Internal cerebral vein asymmetry is an independent predictor of poor functional outcome in endovascular thrombectomy. |
| المؤلفون: |
May Zin Myint, Yeo, Leonard L. L., Tan, Benjamin Y. Q., Ei Zune The, Mei Chin Lim, Ching-Hui Sia, Teoh, Hock-Luen, Sharma, Vijay Kumar, Chan, Bernard, Ahmad, Aftab, Paliwal, Prakash, Gopinathan, Anil, Cunli Yang, Makmur, Andrew, Andersson, Tommy, Arnberg, Fabian, Holmin, Staffan |
| المصدر: |
Journal of NeuroInterventional Surgery; Jul2022, Vol. 14 Issue 7, p683-687, 6p |
| مصطلحات موضوعية: |
EVALUATION of medical care, BLOOD vessels, CONFIDENCE intervals, ISCHEMIC stroke, FUNCTIONAL status, CEREBRAL infarction, THROMBECTOMY, ENDOVASCULAR surgery, COMPUTED tomography, ODDS ratio, CEREBRAL veins, HEMORRHAGE |
| مستخلص: |
Background Endovascular thrombectomy (EVT) in large vessel occlusion (LVO) in anterior circulation acute ischaemic stroke (AIS) results in good functional outcomes in only approximately 60% of the patients. Internal cerebral veins (ICVs) are easily visible, with a consistent midline location, and are linked to stroke outcomes. We hypothesize that ICV asymmetry on multiphasic CT angiogram (mCTA) can be an adjunctive predictor for poor functional outcomes. Methods We studied consecutive AIS patients from 2017 to 2019 with anterior circulation LVO treated with EVT regardless of intravenous thrombolysis. Asymmetrical ICV was defined as the presence of hypodensity (less opacification) on the ipsilateral occlusion side as compared with the contralateral side. The primary outcome was modified Rankin Score (mRS) score at 3 months. Secondary outcomes were good recanalization (modified Thrombolysis In Cerebral Infarction (mTICI) 2b-3), symptomatic hemorrhage, and mortality. results A total of 185 patients were included with a median age of 70 years (IQR 59-77); 87 patients (47%) were female. 82 patients (44.3%) achieved good functional outcomes (mRS 0-2) at 3 months. On multivariate analysis, National Institutes of Health Stroke Scale (NIHSS) (OR 1.076, 95% CI 1.015 to 1.140; p<0.013), poor collateral score (OR 0.285, 95% CI 0.162 to 0.501; p<0.001), asymmetrical ICV on the peak venous phase (OR 2.47, 95% CI 1.115 to 5.471; p<0.026), and late venous phase of the mCTA (OR 2.642, 95% CI 1.161 to 6.016; p<0.021) were independent risks factors of poor outcomes. Conclusion ICV asymmetry is a novel radiological sign which is independently associated with poor functional outcomes in EVT, even after correction for collateral circulation. Further studies are needed to validate this finding. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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