التفاصيل البيبلوغرافية
| العنوان: |
Impact of Hemodialysis on Clinical Outcomes in Patients Undergoing Lower Extremity Bypass Surgery for Peripheral Artery Disease—10-year Follow-Up Study. |
| المؤلفون: |
Kumada, Yoshitaka, Kawai, Norikazu, Ishida, Narihiro, Mori, Akihiro, Ishii, Hideki, Ohshima, Satoru, Ito, Ryuta, Umemoto, Norio, Takahashi, Hiroshi, Murohara, Toyoaki |
| المصدر: |
Angiology; Sep2022, Vol. 73 Issue 8, p744-752, 9p |
| مصطلحات موضوعية: |
LEG surgery, ISCHEMIA, CONFIDENCE intervals, PERIPHERAL vascular diseases, SURGERY, PATIENTS, VASCULAR surgery, TREATMENT effectiveness, DESCRIPTIVE statistics, HEMODIALYSIS, AMPUTATION, LONGITUDINAL method, PROPORTIONAL hazards models |
| مصطلحات جغرافية: |
JAPAN |
| مستخلص: |
We investigated the clinical impact of hemodialysis on long-term outcomes of bypass surgery in patients with peripheral artery disease. We evaluated 660 consecutive patients who underwent successful bypass surgery (392 hemodialysis and 268 non-hemodialysis). The endpoint was amputation-free survival (AFS). To minimize differences in clinical characteristics between the 2 groups, propensity score matching was performed. The AFS rates for 10-year follow-up were 39.3% and 67.7% in hemodialysis and non-hemodialysis patients [hazard ratio (HR) 2.21, 95% confidence interval (CI) 1.65–3.01, P <.0001]. Cumulative incidence of amputation was higher in the hemodialysis group than in the non-hemodialysis group [(19.4 vs 8.4%, HR 2.15, 95% CI 1.29–3.74, P =.0027). In a matched cohort (n = 210 each), AFS was still lower in the hemodialysis patients (53.1 vs 66.3%, HR 1.94, 95% CI 1.36–2.82, P =.0003). However, there was no significant difference in amputation rate between the groups (10.5 vs 10.6%, HR.97, 95% CI 0.49–1.87, P =.93). In a sub-analysis of patients with critical limb ischemia, similar results were obtained. The 10-year AFS was consistently lower in the hemodialysis group than in the non-hemodialysis group. However, the amputation rate was comparable between the groups when matched for the differences in clinical characteristics. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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