دورية أكاديمية

SPIROMETRIC INDICES IN PATIENTS OF COPD ASSOCIATED DIABETES IN RURAL CENTRAL INDIA- A CASE-CONTROL STUDY.

التفاصيل البيبلوغرافية
العنوان: SPIROMETRIC INDICES IN PATIENTS OF COPD ASSOCIATED DIABETES IN RURAL CENTRAL INDIA- A CASE-CONTROL STUDY.
المؤلفون: Singh, Amit, Dhamgaye, Tilak Chand, Ghewade, Babaji, Jadhav, Ulhaas
المصدر: Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research); 2022, Vol. 13 Issue 7, p752-762, 11p
مصطلحات موضوعية: PULMONARY function tests, EXPIRATORY flow, CHRONIC obstructive pulmonary disease, CASE-control method, GLYCEMIC control
مصطلحات جغرافية: INDIA
مستخلص: BACKGROUND: Every complication arising among diabetic patients is secondary to vascular damage thereby affecting the blood supply and leading to ischemic tissue injury. AIM: To determine the difference in Pulmonary Function Tests parameters among diabetic and non-diabetic COPD patients. MATERIAL AND METHODS: This was a hospital-based case-control observational study. We included 103 (50 cases & 53 controls) patients who were diagnosed with COPD and aged more than 40 years. Cases were diabetic patients and controls were nondiabetic patients (based on HB1AC). The PFT was measured by Helios Spirometer subjected to postbronchodilator spirometry evaluation of FEV1, FVC, and FEV1/FVC. RESULTS: The mean FEV1 among the cases and control was 38.60 and 59.54, respectively, p= 0.0001. The mean FVC among cases was 64.46 and among controls was 72.15 (p-value = 0.0001). The mean Peak Expiratory Flow Rate among cases was 191.54 and the control was 257.39 (P-value = 0.0001). The mean FEV1/FVC ratio among cases was 0.59 and controls was 0.64 (P-value = 0.0001). There was a strong but negative correlation between FEV1 and HbA1C (r = -0.866; P-value =0.0001). CONCLUSION: PFT values were significantly lower among diabetic patients in comparison to non-diabetic COPD patients. Moreover, there was a strong and inverse relation between PFT and HbA1C. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index