دورية أكاديمية

Investigation of the association between serum uric acid levels and HEART risk score in patients with acute coronary syndrome.

التفاصيل البيبلوغرافية
العنوان: Investigation of the association between serum uric acid levels and HEART risk score in patients with acute coronary syndrome.
المؤلفون: Khameneh Bagheri, Ramin, Najafi, Mona Najaf, Ahmadi, Mostafa, Saberi, Mohsen, Maleki, Mina, Baradaran Rahimi, Vafa
المصدر: Physiological Reports; Nov2022, Vol. 10 Issue 22, p1-8, 8p
مصطلحات موضوعية: ACUTE coronary syndrome, DISEASE risk factors, URIC acid, CORONARY artery disease, HYPERTENSION risk factors
مستخلص: The association between uric acid (UA) and cardio‐metabolic conditions has been recognized for a long time. However, recently, a body of evidence has highlighted the independent role of UA in a series of conditions, including renal and cardiovascular diseases. In this light, data regarding the prognostic role of UA in acute coronary syndrome (ACS) is scarce. A total number of 100 patients, 59 males and 41 females, diagnosed with ACS were recruited in this study. At the time of admission to the hospital, the serum level of UA was measured. In addition, the HEART score was calculated based on each patients' profile. Participants were on average 61.37 ± 12.08 years old. The most prevalent risk factors were hypertension (48%), a history of coronary artery disease (40%), and diabetes mellitus (33%). The average serum level of UA was 5.81 ± 1.81 mg/dl, and the calculated HEART score had a median of six (minimum of two and maximum of ten). A positive yet statistically insignificant correlation was found between the measured UA level and the calculated HEART score (R = 0.375, p = 0.090). However, further studies with larger sample size are required to assess the direct association of UA level with major adverse cardiac events in patients with cardiovascular disease. [ABSTRACT FROM AUTHOR]
Copyright of Physiological Reports is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
قاعدة البيانات: Complementary Index
الوصف
تدمد:2051817X
DOI:10.14814/phy2.15513