التفاصيل البيبلوغرافية
| العنوان: |
Methyl 5-(2-Fluoro-4-nitrophenyl)furan-2-carboxylate. |
| المؤلفون: |
Mori, Matteo, Tresoldi, Andrea, Cazzaniga, Giulia, Meneghetti, Fiorella, Villa, Stefania |
| المصدر: |
Molbank; Dec2022, Vol. 2022 Issue 4, pM1492, 10p |
| مصطلحات موضوعية: |
ESTER derivatives, IRON, ANTITUBERCULAR agents, MYCOBACTERIUM tuberculosis |
| مستخلص: |
5-Phenyl-furan-2-carboxylic acids have emerged as a new, promising class of antimycobacterial agents that have the ability to interfere with iron homeostasis. Considering the lack of structural data on these compounds, we analyzed the crystal of a fluorinated ester derivative of 5-(4-nitrophenyl)furan-2-carboxylic acid, one of the most potent candidates in the series. Here, we describe the preparation of methyl 5-(2-fluoro-4-nitrophenyl)furan-2-carboxylate (1) and its analysis by 1H-NMR, 13C-NMR, HRMS, and SC-XRD. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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