التفاصيل البيبلوغرافية
| العنوان: |
Endometriosis, the Silent Disease: Molecular Targets, Active Principles, and Drug Delivery Systems. |
| المؤلفون: |
Teworte, Sarah, Luciani, Paola |
| المصدر: |
Helvetica Chimica Acta; Jan2023, Vol. 106 Issue 1, p1-16, 16p |
| مستخلص: |
In this perspective, we provide a broad overview of pathophysiological processes involved in endometriosis, including the role of inflammation, fibrosis, angiogenesis, hormonal regulation, and genetic factors. For each of the functional changes involved with the etiology of the disease, we showcase a selection of active principles in various stages of preclinical and clinical development. Finally, we highlight the role of drug delivery for endometriosis, particularly oral vs. vaginal administration. In doing so, we wish to draw the community's attention to this debilitating disease and highlight the need for interdisciplinary approaches to endometriosis treatment development. [ABSTRACT FROM AUTHOR] |
|
Copyright of Helvetica Chimica Acta is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
Full Text Finder