التفاصيل البيبلوغرافية
| العنوان: |
抗HPV 生物凝胶敷料治疗慢性宫颈炎伴持续性HPV 感染疗效 及对患者疼痛与炎症因子表达的影响. (Chinese) |
| Alternate Title: |
Effect of Anti HPV Biological Gel Dressing on Chronic Cervicitis with Persistent HPV Infection and Its Effect on Pain and Inflammatory Factors Expression. (English) |
| المؤلفون: |
姚艳, 黄琦, 方秀丽, 商晶, 黄秀敏 |
| المصدر: |
Progress in Modern Biomedicine; 2022, Vol. 22 Issue 23, p4461-4422, 5p |
| مصطلحات موضوعية: |
BIOLOGICAL dressings, HUMAN papillomavirus, C-reactive protein, VIRAL load, UTERINE cervicitis |
| Abstract (English): |
Objective: To evaluate the curative effect of anti-HPV biological dressing in the treatment of chronic cervicitis with persistent human papillomavirus (HPV) infection, and analyze the effect on pain and inflammatory factors in patients. Methods: A total of 156 patients with chronic cervicitis and persistent HPV infection who were admitted to our hospital from May 2020 to March 2022 were randomly divided into control group and observation group, 78 cases in each group, and the control group received Baofukang Suppository treatment, the observation group was treated with anti-HPV biological gel dressing. The clinical curative effect, HPV negative conversion rate, pain degree of patients, inflammatory factor levels and other indicators of the two groups were evaluated and compared statistically. Results: Before treatment, there was no significant difference in the indicators between the two groups (P>0.05); after treatment, the pain VAS score of the observation group was significantly lower than that of the control group (P<0.05); α (TNF-α), hypersensitive C-reactive protein (hs-CRP), interleukin (IL)-6 and IL-4 levels were lower than those in the control group (P<0.05), γ-interferon (IFN-γ) After treatment, the viral load of the observation group was lower than that of the control group, and the rate of HPV negative conversion was higher than that of the control group (P<0.05); the total effective rate of the observation group was 96.15%, which was significantly higher than that of the control group. 80.77% of the group (P<0.05). Conclusion: The anti-HPV biological gel dressing is effective in the treatment of chronic cervicitis with persistent HPV infection. It can effectively relieve pain symptoms, increase the rate of HPV negative conversion, improve the local inflammation of the cervix, improve the clinical efficacy, and has good safety. It has clinical promotion [ABSTRACT FROM AUTHOR] |
| Abstract (Chinese): |
评价抗HPV 生物凝胶敷料治疗慢性宫颈炎伴持续性人乳头瘤病毒（HPV)感染的疗效, 并分析对患者疼痛与炎症因 子的影响。方法：选入2020 年5 月~2022 年3 月我院收治的慢性宫颈炎伴持续性HPV 感染患者156 例, 随机分为对照组和观察 组, 每组78 例, 其中对照组予以保妇康栓治疗, 观察组应用抗HPV 生物凝胶敷料治疗。评价两组的临床疗效、HPV 转阴率、患者 疼痛程度、炎症因子水平等指标, 并进行统计比较。结果：治疗前, 两组各项指标无明显差异（P＞0.05)；治疗后, 观察组疼痛VAS 评分显著低于对照组（P＜0.05)；观察组治疗后阴道灌洗液肿瘤坏死因子-琢（TNF-琢)、超敏C 反应蛋白（hs-CRP)、白细胞介素（IL) -6 和IL-4 水平低于对照组（P＜0.05), 酌- 干扰素（IFN-酌)水平高于对照组（P＜0.05)；观察组治疗后病毒载量较对照组低, HPV 转 阴率较对照组高（P＜0.05)；观察组治疗总有效率96.15 %, 显著高于对照组的80.77 %（P＜0.05)。结论：抗HPV 生物凝胶敷料治 疗慢性宫颈炎伴持续性HPV 感染疗效肯定, 可有效缓解疼痛症状, 提高HPV 转阴率, 改善宫颈局部炎症状态, 提升临床疗效, 且 安全性良好, 具有临床推广价值。 [ABSTRACT FROM AUTHOR] |
|
Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
