التفاصيل البيبلوغرافية
| العنوان: |
Merkel Cell Carcinoma. |
| Alternate Title: |
Merkel Hücreli Karsinom. (Turkish) |
| المؤلفون: |
SÖNMEZ ERGÜN, Selma, KİRAZOĞLU, Ahmet, AKDEMİR, Osman Cemil, KÜÇÜK, Özlem Su, ALTINOK, Pelin, YILDIZ, Pelin |
| المصدر: |
Bezmialem Science; 2023, Vol. 11 Issue 1, p128-131, 4p |
| مصطلحات موضوعية: |
MERKEL cell carcinoma, LYMPHADENITIS, MERKEL cells, POLYOMAVIRUSES, CANCER relapse, RHEUMATOID arthritis |
| Abstract (English): |
Merkel cell carcinoma (MCC) is a rare tumor that arises from mechanoreceptor Merkel cells. Ultraviolet exposure, immunosuppression and Merkel cell polyoma virus play a significant role in tumor pathogenesis. Although it typically presents as an initially indolent growing, painless solitary lesion, the course of MCC may be aggressive due to the nodal invasion, distant metastasis and high recurrence rates. We presented a case of MCC with a background history of rheumatoid arthritis treated with immunosuppressive therapy for many years who had necrotizing granulomatous lymphadenitis. [ABSTRACT FROM AUTHOR] |
| Abstract (Turkish): |
Merkel hücreli karsinom (MKK), mekanoreseptör Merkel hücrelerinden kaynaklanan nadir bir tümördür. Ultraviyole maruziyeti, immünosupresyon ve Merkel hücreli polyoma virüsü, tümör patogenezinde önemli bir rol oynamaktadır. Tipik olarak başlangıçta yavaş büyüyen, ağrısız soliter bir lezyon olarak ortaya çıkmasına rağmen, MKK'nin seyri nodal invazyon, uzak metastaz ve yüksek nüks oranları nedeniyle agresif olabilir. Geçmişinde romatoid artrit öyküsü bulunan, uzun yıllardır immünosupresif tedavi gören ve nekrotizan granülomatöz lenfadeniti olan bir MKK olgusunu sunuyoruz. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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