دورية أكاديمية

Outcomes of perineal wound closure techniques after abdominoperineal resections in rectal cancer: an NSQIP propensity score matched study.

التفاصيل البيبلوغرافية
العنوان: Outcomes of perineal wound closure techniques after abdominoperineal resections in rectal cancer: an NSQIP propensity score matched study.
المؤلفون: Cataneo, Jose L., Mathis, Sydney A., del Valle, Diana D., Perez-Tamayo, Alejandra M., Mellgren, Anders F., Gantt Jr., Gerald, Alkureishi, Lee W. T.
المصدر: Journal of Plastic Surgery & Hand Surgery (Medical Journals Sweden) (2020 to 2022); Feb-Dec2023, Vol. 57 Issue 1-6, p399-407, 9p
مصطلحات موضوعية: ABDOMINOPERINEAL resection, PROPENSITY score matching, MUSCULOCUTANEOUS flaps, RECTAL cancer, ONCOLOGIC surgery, RECTUS abdominis muscles, LOGISTIC regression analysis, SURGICAL complications
الشركة/الكيان: AMERICAN College of Surgeons
مستخلص: Perineal defects following abdominoperineal resections (APRs) for rectal cancer may require myocutaneous or omental flaps depending upon anatomic, clinical and oncologic variables. However, studies comparing their efficacy have shown contradictory results. We aim to compare postoperative complication rates of APR closure techniques in rectal cancer using propensity score-matching. The American College of Surgeons Proctectomy Targeted Data File was queried from 2016 to 2019. The study population was defined using CPT and ICD-10 codes for patients with rectal cancer undergoing APR, stratified by repair technique. Perioperative demographic and oncologic variables were controlled for by propensity-score matching. Multivariate logistic regression analysis was performed for wound and major complications (MCs). Of the 3291 patients included in the study, 85% underwent primary closure (PC), 8.3% rectus abdominis myocutaneous (RAM) flap, 4.9% pedicled omental flap with PC, and 1.9% lower extremity (LE) flap repair. Primary closure rates were significantly higher for patients with stage T1 and T2 tumors (p < 0.001). RAM and LE flaps were most used with multi-organ resections, 24% and 25%, respectively (p < 0.001). Similarly, cases with T4 tumors used these flaps more frequently, 30% and 40%, respectively (p < 0.001). After propensity score matching for comorbidities and oncologic variables, there was no significant difference in 30-day postoperative wound or MC rates between perineal closure techniques. The complication rates of the different closure techniques are comparable when tumor stage is considered. Therefore, tumor staging and concurrent procedures should guide clinical decision making regarding the appropriate use of each technique. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:2000656X
DOI:10.1080/2000656X.2022.2144333