دورية أكاديمية

Diagnostic Accuracy of PET/CT in Detecting Aggressiveness of Lymphoma Based on Sub Uptake.

التفاصيل البيبلوغرافية
العنوان: Diagnostic Accuracy of PET/CT in Detecting Aggressiveness of Lymphoma Based on Sub Uptake.
المؤلفون: Waqar, Sana, Siddiqui, Tariq Saeed, Sadiq, Hafsa, Sarfraz, Muhammad Haroon, Sarfraz, Kiran, Mannan, Muhammad
المصدر: Pakistan Armed Forces Medical Journal; Apr-Oct2009, Vol. 73 Issue 2, p494-494, 1p
مصطلحات موضوعية: HODGKIN'S disease, NON-Hodgkin's lymphoma, LYMPHOMAS, BONE marrow, COMPUTED tomography
مصطلحات جغرافية: PAKISTAN
مستخلص: Objective: To determine the diagnostic accuracy of PET/CT in detecting aggressiveness of lymphoma based on sub-uptake keeping bone marrow biopsy as the gold standard. Study Design: Prospective longitudinal study. Place and Duration of Study: Armed Forces Institute of Radiology and Imaging, Rawalpindi Pakistan, from Sep 2020 to Mar 2021. Methodology: One hundred thirty-eight patients of either gender, aged 20 to 80 years who were diagnosed with lymphoma (either Hodgkin's or non-Hodgkin's lymphoma) on initial PET/CT scan were enrolled in the study. All patients underwent PET/CT, and 18-FDG SUV was calculated. After obtaining values, all participants underwent bone marrow biopsy to determine the aggressiveness of lymphoma and findings were subjected to statistical analysis. Results: The mean age of the patients was 54.92±16.86, and the mean SUV value was 17.04±8.03. There were 77(55.8%) males and 61(44.2%) females. Hodgkin's lymphoma was present in 28 (20.3%) patients and non-Hodgkin's lymphoma in 110(79.7%). The sensitivity, specificity, PPV, NPV and diagnostic accuracy of 18 FDG PET/CT SUV were 92%, 92.2%, 93.2%, 90.9% and 92.1%, respectively. Conclusion: 18-FDG PET/CT SUV has high diagnostic accuracy and can detect aggressive lymphomas and further specify the areas for biopsy. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:00309648
DOI:10.51253/pafmj.v73i2.7593