التفاصيل البيبلوغرافية
| العنوان: |
Paravertebral paraganglioma with spinal extension: a case report. |
| المؤلفون: |
Anavi, K., Daya, R., Daya, S., Purbhoo, K., Profyris, C., Mpanza, M. N., Nel, C. E., Bayat, Z. |
| المصدر: |
Journal of Medical Case Reports; 6/8/2023, Vol. 17 Issue 1, p1-9, 9p |
| مصطلحات موضوعية: |
PARAGANGLIOMA, SPINAL cord compression, NEUROENDOCRINE tumors, SPINAL canal, GENETIC mutation, GENETIC testing |
| مستخلص: |
Background: Paragangliomas are rare neuroendocrine tumors. While paragangliomas of the spine are rare, those located in non-cauda equina areas with spinal canal extension are even rarer. Case presentation: We present a case of a 23-year-old female of African descent with a primary thoracic paraganglioma with intervertebral extension resulting in displacement and compression of the spinal cord and extensive local invasion of the surrounding structures. This paraganglioma was functional with typical symptoms of catecholamine excess. Despite the aggressive nature of the paraganglioma, the patient only had isolated sensory symptoms in the left shoulder. Adequate alpha and beta-blockade were instituted prior to her undergoing surgery with near-total resection and complete preserved neurology. There was no underlying pathogenic genetic mutation found. Conclusions: Even though rare, paraganglioma should be considered in the differential diagnosis of spinal tumors. Genetic testing should be performed in patients with paragangliomas. One should exercise extreme caution in treating such rare tumors that may cause neurological deficits and careful surgical planning should be undertaken to avoid possible catastrophic complications. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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