التفاصيل البيبلوغرافية
العنوان: |
Enhancing T‐cell responses to GCB‐like lymphomas with immune‐checkpoint‐blockade‐based therapies. |
المؤلفون: |
Serganova, I., Bucktrout, R., Isshiki, Y., Sarapulov, A., Santella, A., Rodriguez, M., Chakraborty, S., Brunschvig, S., Qualls, D., Vardhana, S., Lesokhin, A., Melnick, A., Beguelin, W., Zappasodi, R. |
المصدر: |
Hematological Oncology; Jun2023 Supplement 1, Vol. 41, p280-280, 1p |
مصطلحات موضوعية: |
T cells, LYMPHOMAS, CYTOTOXIC T cells, REGULATORY T cells |
مستخلص: |
Of note, normal B and/or GCB cells in lymphoma-bearing vs. control mice also downregulated MHC-II, pointing to aberrant B:CD4 SP + sp T-cell interactions overall. B Introduction: b Germinal center B-cell(GCB)-like diffuse large B-cell lymphomas and follicular lymphomas resemble GCB cells, which are normally controlled by CD4 SP + sp T follicular helper (Tfh) cells. Enhancing T-cell responses to GCB-like lymphomas with immune-checkpoint-blockade-based therapies. [Extracted from the article] |
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قاعدة البيانات: |
Complementary Index |