التفاصيل البيبلوغرافية
| العنوان: |
An Observational Study Of Clonidine And Fentanyl As Adjuvants To 0.5% Hyperbaric Bupivacaine In Spinal Anaesthesia In Elective Lower Abdominal Surgeries. |
| المؤلفون: |
Banoo, Shazia, Sharma, Neha, Qadri, Abid Bashir, Banday, Tanveer Rasool |
| المصدر: |
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research); 2023, Vol. 14 Issue 5, p1027-1034, 8p |
| مصطلحات موضوعية: |
CLONIDINE, FENTANYL, ABDOMINAL surgery, BUPIVACAINE, BRACHIAL plexus block, ANESTHESIA, UROLOGICAL surgery |
| مستخلص: |
Background: Regional anaesthesia is the preferred anaesthetic technique in lower extremity, anorectal, urologic, obstetric, and lower abdominal surgeries. Adjuvants such as Morphine, Fentanyl, Clonidine and Dexmedetomidine have been used to supplement intrathecal local anesthetics providing possible advantages. Aim: The aim of this observational study was to evaluate whether intrathecal clonidine and fentanyl could prolong the duration of sensory and motor block during spinal anesthesia and duration of analgesia. Methods: A total of 90 patients of (ASA) physical status I-II of both sexes, aged between 18 and 70 years, were randomly allocated to two groups. Each group consists of 45 patients. Group A: 2.5ml of 0.5% hyperbaric bupivacaine and 50ug of clonidine in 0.5ml of normal saline. Group B: 2.5ml of 0.5% hyperbaric bupivacaine and 25ug of fentanyl in 0.5ml of normal saline. The time of onset and duration of sensory block, highest dermatome level of sensory block, time of onset of motor block, time to complete motor block recovery and duration of spinal anesthesia, intraoperative and postoperative hemodynamics and side effects if any were recorded. VAS, total number of patients who were administered supplemental analgesic in each group and the total amount of supplemental analgesic administered in the next 24 h was quantified and documented. Results: The time of onset of sensory block (min) in groups A and B was 9.10 ± 1.40, and 10.50 ± 1.50 respectively, thus onset of sensory block was not statically significant. Similarly, onset of motor block was also statically insignificant among the study groups. Time of requirement of supplemental analgesia was 212.80 ± 26.32 min and 198.20 ± 21.92 min in group A and B respectively. Duration of analgesia was significantly longer in clonidine group when compared with fentanyl group. Sedation score was more in clonidine group. Conclusion: We conclude that the addition of clonidine in doses of 50 μg and 12.5 μg to low-dose bupivacaine and bupivacaine fentanyl prolongs the sensory and motor block while increasing the duration of postoperative analgesia without significant side-effects. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
