دورية أكاديمية
Synthesis and Antiviral Evaluation of 2′,3′-β- C -Disubstituted Nucleoside Analogue ProTides to Test a Conformational Model of Potency Against Hepatitis C.
| العنوان: | Synthesis and Antiviral Evaluation of 2′,3′-β- C -Disubstituted Nucleoside Analogue ProTides to Test a Conformational Model of Potency Against Hepatitis C. |
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| المؤلفون: | Dentmon, Zackery W., Butch, Christopher J., Gold, Hannah B., Liotta, Dennis C. |
| المصدر: | Synlett; Aug2023, Vol. 34 Issue 13, p1607-1615, 9p |
| مصطلحات موضوعية: | RIBAVIRIN, SCIENTIFIC literature, HEPATITIS C, APPLIED sciences, SILYL group, SILYL ethers |
| مستخلص: | 2014, 58: 3636 20 Zhang, N. Zhang, S. Szostak, J W. J. Am. Chem. Soc. 2012, 134: 3691 21 Kim, S C. Zhou, L. Zhang, W. O'Flaherty, D K. Rondo-Brovetto, V. Szostak, J W. J. Am. Chem. Soc. 2020, 142: 2317 22 Guschlbauer, W. Jankowski, K. Nucleic Acids Res. 1980, 8: 1421 23 Plavec, J. Tong, W. Chattopadhyaya, J. J. Am. Chem. Soc. 1993, 115: 9734 24 Prakash, T P. Chem. Biodivers. Keywords: nucleosides; hepatitis C; prodrugs; antiviral agents; protides; density functional theory EN nucleosides hepatitis C prodrugs antiviral agents protides density functional theory 1607 1615 9 07/31/23 20230815 NES 230815 Graph Nucleosides and nucleotides have long been recognized as privileged chemical structures due to their integral role in life as the monomers of nucleic acids. Synthesis and Antiviral Evaluation of 2',3'- - C -Disubstituted Nucleoside Analogue ProTides to Test a Conformational Model of Potency Against Hepatitis C See: Ashby, E C. Parris, G E. J. Am. Chem. Soc. 1971, 93: 1206 63 Hugelshofer, C L. Palani, V. Sarpong, R. J. Am. Chem. Soc. 2019, 141: 8431 64 Krasovskiy, A. Kopp, F. Knochel, P. Angew. [Extracted from the article] |
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| قاعدة البيانات: | Complementary Index |
| تدمد: | 09365214 |
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| DOI: | 10.1055/a-1904-0249 |