التفاصيل البيبلوغرافية
العنوان: |
SYNTHESIS AND CHARACTERIZATION OF QUERCETIN-LAYER DOUBLE HYDROXIDE (LDH) NANOHYBRID AND THEIR ENHANCED ANTIOXIDANT ACTIVITY. |
المؤلفون: |
Shaji, Y. Christabel, Rose, D. Deena, Kannan, C. Ramesh, Aruna, M., Brucely, Y. |
المصدر: |
Bulletin of the Chemical Society of Ethiopia; 2023, Vol. 37 Issue 4, p917-929, 13p |
مصطلحات موضوعية: |
X-ray powder diffraction, DRUG delivery systems, X-ray diffraction, DIFFRACTION patterns, ION exchange (Chemistry) |
مستخلص: |
This research included the synthesis of pristine nitrate-type Zn2Al-LDH by means of Coprecipitation, which was then followed by hydrothermal treatment. Ion exchange is used to stabilize the produced pristine LDH nano layer, which is used for the encapsulation of bioactive molecules. Quercetin, which has an antioxidant function, is used. XRD was used to investigate the newly synthesized quercetin-LDH (QC-LDH) compound. Quercetin was discovered to be entirely deprotonated as a result of XRD research, and it was also shown to be stabilized in between LDH lattices as a result of electrostatic contact. On the basis of the diphenyl picrylhydrazyl (DPPH) method, the anti-oxidant property was discussed, and it was discovered that the quercetin that was free from the LDH layer helped as an owing antioxidant to scavenge DPPH radicals in ethanol solvent at concentrations ranging from 80-100%, depending on the concentration level. The powder X-ray diffraction patterns indicate that the incorporation of quercetin into the interlayer led to an expansion of the interlayer arrangement to 0.88 and 1.46 nm, respectively. According to the findings of a variety of characterization techniques, the QC-LDH may be regarded as a good antioxidant material with potential drug delivery system. [ABSTRACT FROM AUTHOR] |
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قاعدة البيانات: |
Complementary Index |