التفاصيل البيبلوغرافية
| العنوان: |
Two new chemical constituents from the stem and branch of Tripterygium wilfordii. |
| المؤلفون: |
Hu, Ya-Lin, Hu, Bo, Xu, Tian-Qi, Li, Hong-Yu, Cheng, Huai-Yu, Zhang, Xia, Xu, Wei, Fan, Chun-Lin, Zhou, Guang-Xiong |
| المصدر: |
Journal of Asian Natural Products Research; Sep2023, Vol. 25 Issue 9, p834-841, 8p |
| مصطلحات موضوعية: |
TERPENES, LIGNANS, ANTI-inflammatory agents, PLANT anatomy, AUTOANALYZERS, MACROPHAGES, PHYTOCHEMICALS, RHEUMATOID arthritis, CRYSTALLOGRAPHY, PLANT extracts, MOLECULAR structure, SPECTRUM analysis |
| مستخلص: |
A chemical investigation of 95% ethanol extract from the stem and branch of Tripterygium wilfordii has resulted in the isolation and characterization of two new compounds, one neolignan (1) and one phenylalanine derivative (2), as well as four known compounds (3–6). The structures of the new compounds were determined based on extensive spectroscopic analyses. The absolute configuration of compound 1 was defined by X-ray crystallographic analyses and electronic circular dichroism calculation. In addition, compounds 2 and 4–6 exhibited inhibitory effects against NO production in LPS-induced RAW 264.7 macrophages with the IC50 value ranging from 3.51 μM to 30.40 μM. [ABSTRACT FROM AUTHOR] |
|
Copyright of Journal of Asian Natural Products Research is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
PDF full text from Publisher 
Full Text Finder