التفاصيل البيبلوغرافية
| العنوان: |
Diagnosis of chronic pancreatitis using semi-quantitative MRI features of the pancreatic parenchyma: results from the multi-institutional MINIMAP study. |
| المؤلفون: |
Tirkes, Temel, Yadav, Dhiraj, Conwell, Darwin L., Territo, Paul R., Zhao, Xuandong, Persohn, Scott A., Dasyam, Anil K., Shah, Zarine K., Venkatesh, Sudhakar K., Takahashi, Naoki, Wachsman, Ashley, Li, Liang, Li, Yan, Pandol, Stephen J., Park, Walter G., Vege, Santhi Swaroop, Hart, Phil A., Topazian, Mark, Andersen, Dana K., Fogel, Evan L. |
| المصدر: |
Abdominal Radiology; Oct2023, Vol. 48 Issue 10, p3162-3173, 12p |
| مصطلحات موضوعية: |
CHRONIC pancreatitis, MAGNETIC resonance imaging, PANCREATIC duct, PANCREAS, LOGISTIC regression analysis, DIAGNOSIS, LONGITUDINAL method |
| الشركة/الكيان: |
SIEMENS AG |
| مستخلص: |
Purpose: To determine the diagnostic performance of parenchymal MRI features differentiating CP from controls. Methods: This prospective study performed abdominal MRI scans at seven institutions, using 1.5 T Siemens and GE scanners, in 50 control and 51 definite CP participants, from February 2019 to May 2021. MRI parameters included the T1-weighted signal intensity ratio of the pancreas (T1 score), arterial-to-venous enhancement ratio (AVR) during venous and delayed phases, pancreas volume, and diameter. We evaluated the diagnostic performance of these parameters individually and two semi-quantitative MRI scores derived using logistic regression: SQ-MRI Model A (T1 score, AVR venous, and tail diameter) and Model B (T1 score, AVR venous, and volume). Results: When compared to controls, CP participants showed a significantly lower mean T1 score (1.11 vs. 1.29), AVR venous (0.86 vs. 1.45), AVR delayed (1.07 vs. 1.57), volume (54.97 vs. 80.00 ml), and diameter of the head (2.05 vs. 2.39 cm), body (2.25 vs. 2.58 cm), and tail (1.98 vs. 2.51 cm) (p < 0.05 for all). AUCs for these individual MR parameters ranged from 0.66 to 0.79, while AUCs for the SQ-MRI scores were 0.82 and 0.81 for Model A (T1 score, AVR venous, and tail diameter) and Model B (T1 score, AVR venous, and volume), respectively. After propensity-matching adjustments for covariates, AUCs for Models A and B of the SQ-MRI scores increased to 0.92 and 0.93, respectively. Conclusion: Semi-quantitative parameters of the pancreatic parenchyma, including T1 score, enhancement ratio, pancreas volume, diameter and multi-parametric models combining these parameters are helpful in diagnosis of CP. Longitudinal analyses including more extensive population are warranted to develop new diagnostic criteria for CP. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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