التفاصيل البيبلوغرافية
| العنوان: |
Prevalence and risk factors of SARS-CoV-2 antibody responses among healthcare workers (June 2020–November 2021). |
| المؤلفون: |
Barrufet, Maria Pilar, Serra-Prat, Mateu, Palomera, Elisabet, Ruiz, Alícia, Tapias, Gemma, Montserrat, Noemí, Valladares, Nicolas, Ruz, Francisco Javier, Bolívar-Prados, Mireia, Clavé, Pere |
| المصدر: |
European Journal of Public Health; Oct2023, Vol. 33 Issue 5, p923-929, 7p |
| مصطلحات موضوعية: |
RESEARCH, SEROPREVALENCE, COVID-19, SARS-CoV-2, SCIENTIFIC observation, IMMUNIZATION, SICK people, TIME, COVID-19 vaccines, CORONAVIRUS spike protein, CROSS infection, MEDICAL personnel, ANTIBODY formation, COMPARATIVE studies, TREATMENT effectiveness, DISEASE prevalence, DESCRIPTIVE statistics, VIRAL antibodies, COVID-19 pandemic, LONGITUDINAL method |
| مصطلحات جغرافية: |
SPAIN |
| مستخلص: |
Background To assess SARS-CoV-2 seroprevalence in healthcare workers (HCW) with sampling in June and October 2020 and April and November 2021. Methods Observational and prospective study in 2455 HCW with serum sampling. Antibodies against SARS-CoV-2 nucleocapsid and occupational, social and health risk factors were assessed at each time point. Results Seropositivity for SARS-CoV-2 in HCW increased from 11.8% in June 2020 to 28.4% in November 2021. Of those with a positive test in June 2020, 92.1% remained with a positive test, 6.7% had an indeterminate test and 1.1% had a negative test in November 2021. Non-diagnosed carriers represented 28.6% in June 2020 and 14.6% in November 2021. Nurses and nursing assistants showed the highest prevalence of seropositivity. Close contact (at home or in the hospital) with Covid-19 cases without protection and working in the frontline were the main risk factors. A total of 88.8% HCW were vaccinated, all with a positive serological response in April 2021, but levels of antibodies decreased about 65%, and two vaccinated persons presented a negative serological test against spike protein in November 2021. Levels of spike antibodies were higher in those vaccinated with Moderna compared with Pfizer and the percentage of antibody reduction was higher with Pfizer vaccine. Conclusions This study shows that seroprevalence of SARS-CoV-2 antibodies among HCW doubled that of the general population and that protection both at the workplace and in the socio-familial field was associated with a lower risk of infection, which stabilized after vaccination. [ABSTRACT FROM AUTHOR] |
|
Copyright of European Journal of Public Health is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
Full Text Finder