التفاصيل البيبلوغرافية
| العنوان: |
Coexistence of Amyotrophic Lateral Sclerosis and Alzheimer's Disease: Case Report and Review of the Literature. |
| المؤلفون: |
Verde, Federico, Aiello, Edoardo Nicolò, Adobbati, Laura, Poletti, Barbara, Solca, Federica, Tiloca, Cinzia, Sangalli, Davide, Maranzano, Alessio, Muscio, Cristina, Ratti, Antonia, Zago, Stefano, Ticozzi, Nicola, Frisoni, Giovanni Battista, Silani, Vincenzo |
| المصدر: |
Journal of Alzheimer's Disease; 2023, Vol. 95 Issue 4, p1383-1399, 17p |
| مصطلحات موضوعية: |
AMYOTROPHIC lateral sclerosis, ALZHEIMER'S disease, LITERATURE reviews, REPORTING of diseases, DISEASE duration, APOLIPOPROTEIN E4, CEREBRAL amyloid angiopathy |
| مستخلص: |
We describe a case of amyotrophic lateral sclerosis (ALS) associated with Alzheimer's disease (AD) and review the literature about the coexistence of the two entities, highlighting the following: mean age at onset is 63.8 years, with slight female predominance; ALS tends to manifest after cognitive impairment and often begins in the bulbar region; average disease duration is 3 years; cognitive phenotype is mostly amnestic; the pattern of brain involvement is, in most cases, consistent with AD. Our case and the reviewed ones suggest that patients with ALS and dementia lacking unequivocal features of FTD should undergo additional examinations in order to recognize AD. [ABSTRACT FROM AUTHOR] |
|
Copyright of Journal of Alzheimer's Disease is the property of IOS Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
