التفاصيل البيبلوغرافية
| العنوان: |
Organocatalyzed Regioselective α,γ-Difunctionalization of Deconjugated Butenolides: Synthesis of Butyrolactone–Butyrolactam Hybrid Molecules. |
| المؤلفون: |
Mondal, Swati Lekha, Patra, Koushik, Yadav, Rahul, Baidya, Mahiuddin |
| المصدر: |
Synlett; Dec2023, Vol. 34 Issue 20, p2465-2470, 6p |
| مصطلحات موضوعية: |
BUTENOLIDES, MOLECULES, PHARMACEUTICAL chemistry, BUTYROLACTONES, CARBONYL compounds |
| مستخلص: |
This article discusses the synthesis of hybrid molecules that contain both γ-butyrolactone and γ-butyrolactam motifs, which are important in pharmaceutical science. The authors developed a method for regioselective difunctionalization of deconjugated butyrolactones using α-amide enones as Michael acceptors, resulting in high yields and excellent diastereoselectivity. The study provides a simple and efficient approach to the synthesis of these hybrid molecules. Additionally, the article briefly mentions the celebration of Yamamoto's 80th birthday, but does not provide any further details about the event or Yamamoto himself. [Extracted from the article] |
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| قاعدة البيانات: |
Complementary Index |
