التفاصيل البيبلوغرافية
| العنوان: |
Hospital admissions associated with dehydration in childhood kidney transplantation. |
| المؤلفون: |
Le Page, Amelia K., Johnstone, Lilian M., Kausman, Joshua Y. |
| المصدر: |
Pediatric Nephrology; Feb2024, Vol. 39 Issue 2, p547-557, 11p |
| مصطلحات موضوعية: |
DEHYDRATION -- Risk factors, GRAFT rejection, CONFIDENCE intervals, DRINKING (Physiology), AGE distribution, KIDNEY transplantation, TERTIARY care, REGRESSION analysis, RETROSPECTIVE studies, ACQUISITION of data, RISK assessment, HOSPITAL care, DESCRIPTIVE statistics, MEDICAL records, DEHYDRATION, CHILDREN |
| مستخلص: |
Background: Paediatric kidney transplant recipients may be at a particular risk of dehydration due to poor kidney concentrating capacity and illness associated with poor fluid intake or losses. In this population, creatinine rise may be more likely with relatively mild dehydration, which may trigger hospital admission. This study describes hospital admissions in the first 12 months after transplantation with diagnosis of graft dysfunction associated with dehydration due to illness or poor fluid intake. We assess risk factors for these admissions. Methods: Data was extracted from medical records of patients transplanted in two tertiary children hospitals. Following descriptive analysis, multiple failure regression analyses were used to identify factors associated with admission for acute kidney allograft dysfunction associated with dehydration. Results: Of 92 children, 42% had at least 1 dehydration admission in the 12 months following transplantation. Almost half of the dehydration admissions were due to poor fluid intake, which accounted for 1/5 of all unplanned hospital admissions. Target fluid intake at first discharge of > 100 ml/kg/day was associated with dehydration admissions of all types (hazard ratio (HR) 2.04 (95% CI 1.13–3.68)). Teen age was associated with poor fluid intake dehydration admissions (HR 4.87 (95% CI 1.19–19.86)), which were more frequent in mid-summer. Use of enteric feeding tube, which correlated with age under 4, associated with contributing illness dehydration admissions (HR 2.18 (95% CI 1.08–4.41)). Conclusions: Dehydration admissions in the 12 months following childhood kidney transplantation are common. Highlighted admission risk factors should prompt further study into optimal fluid intake prescription and hydration advice given to children, teenagers, and their carers following kidney transplantation. Use of an enteric feeding tube may not protect patients from admission with dehydration associated with contributing illness. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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