التفاصيل البيبلوغرافية
| العنوان: |
Identification of IncA Plasmid, Harboring bla VIM-1 Gene, in S. enterica Goldcoast ST358 and C. freundii ST62 Isolated in a Hospitalized Patient. |
| المؤلفون: |
Piccirilli, Alessandra, Di Marcantonio, Sascia, Costantino, Venera, Simonetti, Omar, Busetti, Marina, Luzzati, Roberto, Principe, Luigi, Di Domenico, Marco, Rinaldi, Antonio, Cammà, Cesare, Perilli, Mariagrazia |
| المصدر: |
Antibiotics (2079-6382); Dec2023, Vol. 12 Issue 12, p1659, 13p |
| مصطلحات موضوعية: |
INCAS, HOSPITAL patients, ACUTE myeloid leukemia, SALMONELLA enterica serovar Typhi, GENES |
| مستخلص: |
In the present study, we analyzed the genome of two S. enterica strains TS1 and TS2 from stool and blood cultures, respectively, and one strain of C. freundii TS3, isolated from a single hospitalized patient with acute myeloid leukemia. The S. enterica Goldcoast ST358 (O:8 (C2-C3) serogroup), sequenced by the MiSeq Illumina system, showed the presence of β-lactamase genes (blaVIM-1, blaSHV-12 and blaOXA-10), aadA1, ant(2″)-Ia, aac(6′)-Iaa, aac(6′)-Ib3, aac(6′)-Ib-cr, qnrVC6, parC(T57S), and several incompatibility plasmids. A wide variety of insertion sequences (ISs) and transposon elements were identified. In C. freundii TS3, these were the blaVIM-1, blaCMY-150, and blaSHV-12, aadA1, aac(6′)-Ib3, aac(6′)-Ib-cr, mph(A), sul1, dfrA14, ARR-2, qnrVC6, and qnrB38. IncA plasmid isolated from E.coli/K12 transconjugant and C. freundii exhibited a sequence identity >99.9%. The transfer of IncA plasmid was evaluated by conjugation experiments. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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