التفاصيل البيبلوغرافية
| العنوان: |
Deubiquitinating enzymes for targeted cancer therapy. |
| المؤلفون: |
Li, Yue, Wang, Xiaohui |
| المصدر: |
Clinical & Translational Discovery; Dec2023, Vol. 3 Issue 6, p1-8, 8p |
| مصطلحات موضوعية: |
DEUBIQUITINATING enzymes, CANCER treatment, UNIVERSITIES & colleges, MEDICAL schools, ACADEMIC programs |
| مصطلحات جغرافية: |
JIANGSU Sheng (China), CHINA |
| مستخلص: |
This article provides an overview of deubiquitinating enzymes (DUBs) and their role in targeted cancer therapy. It specifically focuses on the DUB OTUB1 and its regulation of CCN6, a tumor suppressor in breast cancer. The article discusses the potential of DUBs as therapeutic targets for cancer treatment, but highlights the need for caution due to the diverse functions of OTUB1 in different cancer types. The article also summarizes different strategies for manipulating the expression and activities of DUBs. The study was conducted by Zhao et al. and acknowledges support from Suzhou Medical College of Soochow University and the Priority Academic Program Development of the Jiangsu Higher Education Institutions of China. [Extracted from the article] |
|
Copyright of Clinical & Translational Discovery is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
Full Text Finder