التفاصيل البيبلوغرافية
| العنوان: |
Lipid composition of blood plasma and epithelium of the jejunal mucosa in calves with dyspepsia and its correction. |
| المؤلفون: |
Gryshchenko, V. A., Danchenko, O. О., Tkachuk, S. A., Fotina, T. I., Zazharskyi, V. V., Brygadyrenko, V. V. |
| المصدر: |
Regulatory Mechanisms in Biosystems; 2023, Vol. 14 Issue 2, p319-324, 6p |
| مصطلحات موضوعية: |
BLOOD plasma, INDIGESTION, PHOSPHOLIPIDS |
| مستخلص: |
Enteropathology in newborn ruminants significantly affects the functional formation of the digestive tract, which induces complications in other organs and systems, reducing the resistance and productivity in recovered animals. It is also characterized by metabolic disorders, particularly lipids, which adversely affects the regenerative processes at the cellular level. The material for the study was 2-day-old calves, from which 3 groups of 6 animals each were formed. 1st group – control was made up of clinically healthy animals, 2nd group – calves with toxic dyspepsia which received traditional treatment and 3rd group – calves which were additionally orally administered a liposomal form of a 1% solution of BAD "FLP-MD". The lipid composition of blood plasma and the epithelium of the mucous membrane of the jejunum of calves was studied by the method of thin-layer chromatography on standard Silufol plates. The lipidogram of blood plasma in 30-day-old calves recovered from dyspepsia under traditional treatment regimen was characterized by dyslipidemia, which was manifested by an increase in total lipid content by 10.0% amid hypercholesterolemia and hypertriacylglycerolemia and a decrease in free fatty acids by 24.6% and phospholipids by 11.8%. Also, phosphatidylcholine and sphingomyelin content decreasesd in the blood plasma. In epithelium of the jejunal mucosa, total lipid content decreased due to total cholesterol, triacylglycerols, and phospholipids. The restoration of total lipid content and individual fractions was found in blood plasma of calves that received additionally phospholipid-containing bio-additive "FLP-MD".Among the individual phospholipids phosphatidylcholine, phosphatidylethanolamine and phosphatidylserine prevailed. In these calves, most of the lipid components in the epithelium of the jejunal mucosa were stabilized. In the future, we plan to investigate the content of total lipids in the blood and mucous membrane of the small intestine of calves. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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