التفاصيل البيبلوغرافية
| العنوان: |
Determination of Acetaminophen (Paracetamol) by Tranexamic Acid Modified Glassy Carbon Electrode. |
| المؤلفون: |
İslamoğlu, Nesim, Mülazımoğlu, Ayşen Demir |
| المصدر: |
Analytical & Bioanalytical Electrochemistry; Dec2023, Vol. 15 Issue 12, p1086-1097, 12p |
| مصطلحات موضوعية: |
CARBON electrodes, TRANEXAMIC acid, ELECTRODE performance, ELECTROCHEMICAL electrodes, SCANNING electron microscopes, ACETAMINOPHEN, ANALGESICS |
| مستخلص: |
In this study, tranexamic acid (Txa) (in 0.1 M Sulfuric acid) modified glassy carbon electrode (GC) was tested, for the first time, as a sensor for determining the most consumed pain reliever, paracetamol (ACOP) by differential pulse voltammetry (DPV). The tranexamic acid-modified glassy carbon (rTxa/GC) electrode was characterized by a scanning electron microscope (SEM). Cyclic voltammetry (CV), linear sweep voltammetry (LSV), and electrochemical impedance spectroscopy (EIS) (in aqueous and nonaqueous solution) were used to evaluate the electrochemical performance of electrodes. The modified electrode increased the oxidation peak current of ACOP significantly in this case. The experimental results provide that rTxa/GC electrode displayed excellent electrocatalytic response to the oxidation ACOP. Additionally, the rTxa/GC electrode exhibited excellent electrocatalytic activity for the electrochemical determination of ACOP in Britton-Robinson (BR) buffer solution with pH values ranging from 2 to 12. As a result, the effective electroactive surface area of rTxa/GC electrode increased by using a BR buffer solution with pH 6. The linear range was 25 - 80 µM for ACOP with a limit of detection (LOD) of 4.7 µM and a limit of detection (LOQ) of 14.2 µM. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
