التفاصيل البيبلوغرافية
| العنوان: |
Epidemiological analysis reveals a surge in inflammatory bowel disease among children and adolescents: A global, regional, and national perspective from 1990 to 2019 - insights from the China study. |
| المؤلفون: |
Zhong-mian Zhang, Zi-li Lin, Bai-xiang He, Wei-tian Yan, Xi-yan Zhang, Zhong-han Zhang, Lan Wang, Jia-qi Wang, Da-ming Liu, Wen Zhang, Zhi-hong Li |
| المصدر: |
Journal of Global Health; 2023, Vol. 13, p1-15, 15p |
| مصطلحات موضوعية: |
RESEARCH, MEDICAL quality control, INFLAMMATORY bowel diseases, CONFIDENCE intervals, HEALTH services accessibility, GLOBAL burden of disease, LIFE expectancy, AGE distribution, POPULATION geography, DISEASE incidence, DISEASE prevalence, DESCRIPTIVE statistics, RESEARCH funding, PEOPLE with disabilities, STATISTICAL correlation, SOCIODEMOGRAPHIC factors, DATA analysis software, CHILDREN, ADOLESCENCE |
| مستخلص: |
Background The burden of inflammatory bowel disease (IBD) among children and adolescents is rising globally, with substantial variation in levels and trends of disease in different countries and regions, while data on the burden and trends were sparse in children and adolescents. We aimed to assess the trends and geographical differences in children and adolescents aged zero to 19 in 204 countries and territories over the past 30 years. Methods Data on IBD among children and adolescents was collected from the Global Burden of Disease (GBD) 2019 database from 1990 to 2019. We used the GBD data and methodologies to describe the change in the burden of IBD among children and adolescents involving prevalence, incidence, disability-adjusted life years (DALYs), and mortality. Results Globally, the IBD prevalence cases increased between 1990 and 2019. Annual percentage changes (AAPC) = 0.15; 95% confidence interval (CI) = 0.11-0.19, and incidence cases of IBD increased from 20 897.4 (95% CI = 17 008.6-25 520.2 in 1990 to 25 658.6 (95% CI = 21 268.5-31 075.6) in 2019, representing a 22.78% increase, DALYs cases decreased between 1990 and 2019 (AAPC = -3.02; 95% CI = -3.15 to -2.89), and mortality cases of IBD decreased from 2756.5 (95% CI = 1162.6-4484.9) in 1990 to 1208.0 (95% CI = 802.4-1651.4) in 2019, representing a 56.17% decrease. Decomposition analysis showed that IBD prevalence and incidence increased significantly, and a trend exhibited a decrease in underlying age and population-adjusted IBD DALYs and mortality rates. Correlation analysis showed that countries with high health care quality and access (HAQ) had relatively higher IBD age-standardised prevalence rate (ASPR) and age-standardised incidence rate (ASIR), but lower age-standardised DALYs rate (ASDR) and age-standardised mortality rate (ASMR). Conclusions Global prevalence and incidence rate of IBD among children and adolescents have been increasing from 1990 to 2019, while the DALYs and mortality have been decreasing. Rising prevalence and rising incidence in areas with historically low rates will have crucial health and economic implications. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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