التفاصيل البيبلوغرافية
| العنوان: |
Association analysis of polymorphisms at GLRB, GRIA2, and GASK1B genes with reproductive traits in Dazu Black Goats. |
| المؤلفون: |
Fang, Xingqiang, Yang, Songjian, Chen, Meixi, Sun, Ruifan, Zhao, Le, Gu, Bowen, Zhang, Jipan, Huang, Deli, Zheng, Taikang, Zhao, Yuanping, Peng, Peng, Zhao, Yongju |
| المصدر: |
Animal Biotechnology; Dec2023, Vol. 34 Issue 9, p4721-4729, 9p |
| مصطلحات موضوعية: |
SINGLE nucleotide polymorphisms, GOATS, GENES, GOAT breeds, LOCUS (Genetics) |
| مستخلص: |
Reproductive traits are essential economic traits in goats. This study aimed to analyze the relationship between single nucleotide polymorphisms (SNPs) within the genes of GLRB, GRIA2, and GASK1B, and reproductive traits (kidding traits and placental traits) in goats. We used the resequencing data of 150 Dazu Black Goats to perform correlation analysis with the average litter size. We screened thirteen SNPs loci in introns and then used the Sanger method to genotype the remaining 150 Dazu Black Goats. The results showed that a total of six SNPs were screened. Three SNPs related to litter size and live litter size (g.28985790T > G, g.28986352A > G, and g.28987976A > G); one SNP related to total cotyledon area (g.29203243G > A); two SNPs related to placental efficiency (g.30189055G > A and g.30193974C > T); one SNP associated with cotyledon support efficiency (g.30193974C > T). The qPCR results showed that GLRB, GRIA2, and GASK1B were all highly expressed in the udder, kidney, uterus, and ovary. It indicated that these three candidate genes might affect the reproductive traits, which could be used as candidate markers for reproductive traits in Dazu Black Goats. Moreover, association studies on a large scale are still needed to figure out what effect these SNPs have on reproductive traits. [ABSTRACT FROM AUTHOR] |
|
Copyright of Animal Biotechnology is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
PDF full text from Publisher 
Full Text Finder